DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gus and fsn-1

DIOPT Version :9

Sequence 1:	NP_001246140.1	Gene:	gus / 35478	FlyBaseID:	FBgn0026238	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	NP_498046.1	Gene:	fsn-1 / 175667	WormBaseID:	WBGene00001499	Length:	332	Species:	Caenorhabditis elegans

Alignment Length:	193	Identity:	81/193 - (41%)
Similarity:	118/193 - (61%)	Gaps:	10/193 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 ILLDMPPASRDLQLKH-SWNSEDRSLNIFVKEDDKLTFHRHPVAQSTDCIRGKVGLTKGLHIWEI 104
            :|.::..|.:.|:..: :||:.|.|.|.:::.:. .|.||.|||||||.:|||.|::||:|.::|
Worm   142 LLAELGSAKKKLRAWYFAWNTSDISRNNYIRTNG-FTVHRQPVAQSTDGVRGKRGISKGVHAFDI 205

  Fly   105 YW--PTRQRGTHAVVGVCTADAPLHSVGYQSLVGSTEQSWGWDLGRNKLYHDSKNCAGVTYPAIL 167
            .|  |.   ||.||||:.|..|.||.|||.:|:||.:|||||:|..|.|.|:... .|| ||. :
Worm   206 TWDGPL---GTVAVVGIATKHAALHCVGYVALLGSDDQSWGWNLVDNVLMHNGAQ-LGV-YPK-M 264

  Fly   168 KNDEAFLVPDKFLVALDMDEGTLSFIVDQQYLGIAFRGLRGKKLYPIVSAVWGHCEITMRYIG 230
            .|...:.|.||..:.:|.|.....|..:.::|||||..:...:|||.|.||:|:.|:||.|:|
Worm   265 NNPPKYEVGDKIRLIIDCDTHVAYFERNSEFLGIAFNHIPPLRLYPAVCAVYGNTEVTMVYVG 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gus	NP_001246140.1	SPRY_SOCS1-2-4	56..229	CDD:293963	76/175 (43%)
gus	NP_001246140.1	SOCS_SSB1_4	234..276	CDD:239688
fsn-1	NP_498046.1	F-box	83..127	CDD:279040
fsn-1	NP_498046.1	SPRY_Fbox	158..332	CDD:293964	78/177 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3953
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D399707at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820