DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gus and fbxo45

DIOPT Version :9

Sequence 1:	NP_001246140.1	Gene:	gus / 35478	FlyBaseID:	FBgn0026238	Length:	279	Species:	Drosophila melanogaster
Sequence 2:	XP_012825639.1	Gene:	fbxo45 / 100216147	XenbaseID:	XB-GENE-972343	Length:	282	Species:	Xenopus tropicalis

Alignment Length:	203	Identity:	81/203 - (39%)
Similarity:	127/203 - (62%)	Gaps:	14/203 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RIDILLDMPPASRDLQ-LKHSWNSEDRSLNIFVKEDDKLTFHRHPVAQSTDCIRGKVGLTKGLHI 101
            |.|||.::|.....:: .:|.::|.|.|.|:::|::. .|.||:|:|||||..|.|:|.::|.|.
Frog    89 RTDILCNLPTYKAKMRAFQHGFSSSDCSRNVYIKKNG-FTLHRNPIAQSTDGARTKIGFSEGRHA 152

  Fly   102 WEIYW--PTRQRGTHAVVGVCTADAPLHSVGYQSLVGSTEQSWGWDLGRNKLYHDSKNCAGVTYP 164
            ||::|  |.   ||.||:|:.|..||:...||.:|:||.:|||||:|..|.|.|:.:  ...::|
Frog   153 WEVWWEGPL---GTVAVIGIATKRAPMQCQGYVALLGSDDQSWGWNLVDNNLLHNGE--VNGSFP 212

  Fly   165 AILKNDEAFLVPDKFLVALDMDEGTLSFIVDQQYLGIAFRGLRGKKLYPIVSAVWGHCEITMRYI 229
            . ..|...:.:.::..|.|||::.||:|....::||:|||||....|||.||||:|:.|:|:.|:
Frog   213 Q-CNNAPKYQIGERIRVILDMEDKTLAFERGYEFLGVAFRGLPKTCLYPAVSAVYGNTEVTLVYL 276

  Fly   230 GGLDPEPL 237
            |    :||
Frog   277 G----KPL 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gus	NP_001246140.1	SPRY_SOCS1-2-4	56..229	CDD:293963	72/174 (41%)
gus	NP_001246140.1	SOCS_SSB1_4	234..276	CDD:239688	2/4 (50%)
fbxo45	XP_012825639.1	F-box-like	34..79	CDD:372399
fbxo45	XP_012825639.1	SPRY_Fbox	108..282	CDD:293964	76/184 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910