Protein Alignment CG3107 and SDD3

DIOPT Version :9

• Sequence 1: NP_001036470.1
• Gene: CG3107 / 35475
• FlyBaseID: FBgn0033005
• Length: 1034
• Species: Drosophila melanogaster
• Sequence 2: NP_014543.1
• Gene: SDD3 / 854055
• SGDID: S000005458
• Length: 1037
• Species: Saccharomyces cerevisiae
• Alignment Length: 1078
• Identity: 228/1078 - (21%)
• Similarity: 426/1078 - (39%)
• Gaps: 234/1078 - (21%)

  Fly    79 EHISEFELTSYTFRYERTGTELWHIDRNDS---NNVFSINFRTTPFDSTGLPHILEHLSLCGSQK 140
            :::.::.:|.|.  .|||..:|.||:...|   :..|::  .|...:.:|.||.||||...||:.
Yeast    12 DYVPQYHITKYI--SERTKLQLVHINHKTSPLVHGYFAV--PTECLNDSGAPHTLEHLIFMGSKS 72

  Fly   141 YPVRDPFFKMLNRSVATFMNAMTGPDYTIYPFSTMNEIDFRNLQHIYLDAVFRPNLAYFDFLQEG 205
            ||.:.......|.|::. .||.|..|.|:|..|:.....|..|...|||.:..|.|.....|.|.
Yeast    73 YPYKGLLDTAGNLSLSN-TNAWTDTDQTVYTLSSAGWKGFSKLLPAYLDHILHPTLTDEACLTEV 136

  Fly   206 WRLENKDIFDKQSKLVIKGVVYNEMKGAFSENAQVFSQNLLNNIFPDHT-YRHVSGGNPLEIPKL 269
            :.::.:::.|       ||||::||:...::...:........:||:.: ||..:||....:..|
Yeast   137 YHIDPENLGD-------KGVVFSEMEAIETQGWYISGLEKQRLMFPEGSGYRSETGGLTKNLRTL 194

  Fly   270 AYNDLVEFHKKYYHPSNARIYSYGLFDASKTLALLDEEYLSDQSWVDNSY----SLIRQQERWTQ 330
            ..:::.:|||..|...|..:...|.....:.|.:::|       | ||..    |.|.::..:..
Yeast   195 TNDEIRQFHKSLYSSDNLCVIVCGNVPTDELLTVMEE-------W-DNKLPEIPSNIPKKRPFLD 251

  Fly   331 PRLVHISSRLDNM-GTTI------DRQNQIAIALLMCDATNIQESFELHVLSEVLIRGPNSPFYK 388
            .:|.||....|.: .:|:      :.|.::..:.:....::.:....:.||.:.......:.|.:
Yeast   252 NKLSHIPQSRDKVTESTVEFPELDESQGELLFSWIGVPYSDFRNDLAVDVLLDYFTDSALAVFTR 316

  Fly   389 NLIEPNFSGGYNQTTGYSSDTKDTTFVVGLQDLRVEDF---------KKCIEIFDKTIINSMNDG 444
            .|:|      .:.....|:|.....|:..:.|||::..         .|.:||.....|
Yeast   317 ELVE------IDDPMANSTDCCTDYFMRTIIDLRIQGVPTEKIAATKTKVLEILKTHTI------ 369

  Fly   445 FDSQHVESVLHNLE----LSLKHQNPNFGNTLLFNSTALWNHDG-DVVSNLR-VSDMISGLRESI 503
             |...|..|:.|.:    |:.:....:..::.:.......|.|| .:||:|: :||..:.|:.|
Yeast   370 -DLSRVRQVVENTKWEYLLNYEKNGESRFSSAVITDYIYGNEDGSSLVSSLKDLSDFDALLQWS- 432

  Fly   504 SQNKKYFQEKIEKYFANNNHRLTLTMSPDE-AYE-------DKFKQAELELVEQK----VKLLDE 556
               :|.:|..:.:.|.:|. .:.:|..|.. .||       |..||.|.|..::|    :|.|:.
Yeast   433 ---QKDWQSLLNRIFVDNK-PIIVTAKPSALMYEQLEKEKSDLIKQREAEFDDEKKLVLLKRLNN 493

  Fly   557 VKIEKIYERGLILDSYQKAE----------SNTDLLPCL---TMNDVRDP---------PKWPKL 599
            .|  .|.:|.:.....||.|          .||..:..:   ..|:|.||         |....|
Yeast   494 AK--NINDRPIPKSLLQKFEIDNPSKSVEFVNTKSIATVDSYKYNNVSDPLTKKILETRPDNFPL 556

  Fly   600 FIQNVQNVRTQICKVPTNEITYFKCMFNITGLSHEETQLMPLFCNVISAMGTTNYNYREFDK--- 661
            || ::.:..:|          :.:..|.:...|.::|.|:|.|              ..||:
Yeast   557 FI-HLNHFPSQ----------FIELHFLVNSASIKDTSLLPYF--------------NMFDELFS 596

  Fly   662 ---HILLKTGGFDFKLHLIEDVRDSKSYSLSVMINTHALNNNVPEMFAL---CQ--------ELI 712
               .||.:....:..|...|.|...||.::...|| ..|..:.|::...   |:        :.|
Yeast   597 MPMKILDEESNVETMLSFEEVVAKLKSETIDAQIN-QGLKGSCPDLINFKIQCRAGGYSNSVQWI 660

  Fly   713 KNVRFD---DSERLKMLIENYISYI-------SVGVAS--SGHLY---AMLGATSQVCDAGKLKS 762
            |:..||   |..|:::|:|||::.|       :|.::|  :.:||   ::..:|..:....||:.
Yeast   661 KHCLFDMVFDENRVRILLENYLNSIVEWKRNGNVMLSSLTNRNLYSARSLKKSTDPLFVEAKLQE 725

  Fly   763 LLYGVDHIDFMKNFVHSTSTVDICDKLSTIASKV---FNK-------------------DNMRGA 805
            :...:::.:|.|         :|..::.|:..::   |||                   :.:...
Yeast   726 IFAEIENGNFEK---------EILPRIETMRKQLRANFNKFHILVLGDISKIDDVYEPWNPLIKC 781

  Fly   806 INTTQSYEPSAISNYEKFLESLPTFGKTQTSRNIHYLDPSCQQYVMNIPVNYCAKALFTVPY-LH 869
            :|.....|...|....:.|:::.:..:|...:......|:.:...||:        :.::|: |.
Yeast   782 LNIAHPVEKLKIPPVPRALDTISSICRTPGEKAFIITTPASESAYMNL--------ITSIPFNLD 838

  Fly   870 QDHPTLRVLAKLLSAKYLLPV-------IREKNGAYGAG-AKISSDGIFSFYSYRDPNSTKTLNA 926
            ...|...:::  |:::||..|       ||....||||. .|:.....:.|..||..:..|....
Yeast   839 YHDPEYAIVS--LASEYLECVEGPFWKGIRGAGLAYGASMLKLCEINSWGFNIYRGADIIKCYEV 901

  Fly   927 FDETYKWLRANQNVIDQQSLFESKLGVLQQLDTPIAPGNIGIDYFLYEVSQ--EDF--------- 980
            ..:..:...:.....|:|.:..:...::.:|.|      |...||...:|:  ::|
Yeast   902 GKQIVQDYASGALEFDEQLIQGAISSIINRLAT------IECGYFETALSKYVDEFCLQRGNNFN 960

  Fly   981 ESYRSRMLSVTIDDLQCAIENYF-----GKESMHYGKC 1013
            |.|..|:.:||..||:.|::.||     ..:|:.:..|
Yeast   961 ELYLERLQNVTKTDLKNAMQKYFVNMFDSNKSVAFVSC 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3107	NP_001036470.1	Cym1	68..1003	CDD:223957	224/1061 (21%)
		Peptidase_M16	120..>177	CDD:279066	20/56 (36%)
		Peptidase_M16_C	268..457	CDD:282978	38/208 (18%)
		M16C_assoc	531..773	CDD:285556	66/307 (21%)
SDD3	NP_014543.1	Cym1	1..1017	CDD:223957	228/1078 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1026
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1786
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R283
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.790