DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC41C and CAPS2

DIOPT Version :9

Sequence 1:	NP_001246139.1	Gene:	TpnC41C / 35473	FlyBaseID:	FBgn0013348	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	XP_006719711.2	Gene:	CAPS2 / 84698	HGNCID:	16471	Length:	614	Species:	Homo sapiens

Alignment Length:	155	Identity:	36/155 - (23%)
Similarity:	65/155 - (41%)	Gaps:	23/155 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SDELT-----KEQTALLRNAFNAFDPEKNGYINTAMVGTILSMLGHQLDDATLADIIAEVDEDGS 61
            ||.|:     ||.| ||:......|......:.||.:        .|.||.    ||.|.::
Human   376 SDHLSLPESIKENT-LLKLRITNIDQIALDSLKTASM--------EQEDDI----IIQETND--- 424

  Fly    62 GQIEFEEFTTLAARFLVEEDAEAMMAELKEAFRLYDKEGNGYITTGVLREILRELDDKLTNDDLD 126
             ::.|:....:....|.:.... ::..|.:.|:..||||||.:.....::.|:....:::..|.:
Human   425 -RLVFKAIQDVLKEKLHKRGVR-ILTGLGKYFQQLDKEGNGLLDKADFKQALKVFHLEVSEKDFE 487

  Fly   127 MMIEEIDSDGSGTVDFDEFMEVMTG 151
            .....::.:|:|.||:.||...:.|
Human   488 SAWLILNDNGNGKVDYGEFKRGIIG 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC41C	NP_001246139.1	PTZ00184	1..150	CDD:185504	35/152 (23%)
CAPS2	XP_006719711.2	YajQ_like	<408..>444	CDD:294471	10/51 (20%)
		EF-hand_7	450..510	CDD:290234	16/59 (27%)
		EFh	454..510	CDD:238008	15/55 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148548
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930