DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TpnC41C and EFCAB6

DIOPT Version :9

Sequence 1:	NP_001246139.1	Gene:	TpnC41C / 35473	FlyBaseID:	FBgn0013348	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	XP_011528618.1	Gene:	EFCAB6 / 64800	HGNCID:	24204	Length:	1613	Species:	Homo sapiens

Alignment Length:	168	Identity:	36/168 - (21%)
Similarity:	66/168 - (39%)	Gaps:	35/168 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 RNAFNAF---DPEKNGYINTAMVGTILSMLGHQLDDATLADIIAEVDEDGSGQIEFEEFTTL--- 72
            |:.::||   |.:::|.||...:..:|..|...|.|......:..:....|..:.|.||..|
Human   770 RDPYSAFFKTDADRDGIINMHDLHRLLLHLLLNLKDDEFERFLGLLGLRLSVTLNFREFQNLCEK 834

  Fly    73 ----------------------------AARFLVEEDAEAMMAELKEAFRLYDKEGNGYITTGVL 109
                                        |.::||.: |:...::|.:.|...|.||||.:....:
Human   835 RPWRTDEAPQRLIRPKQKVADSELACEQAHQYLVTK-AKNRWSDLSKNFLETDNEGNGILRRRDI 898

  Fly   110 REILRELDDKLTNDDLDMMIEEIDSDGSGTVDFDEFME 147
            :..|...|..||..:.:.:....|::|.|.:.:.||::
Human   899 KNALYGFDIPLTPREFEKLWARYDTEGKGHITYQEFLQ 936

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC41C	NP_001246139.1	PTZ00184	1..150	CDD:185504	36/168 (21%)
EFCAB6	XP_011528618.1	EFh	100..152	CDD:298682
		EF-hand_7	203..261	CDD:290234
		EFh	203..261	CDD:298682
		FRQ1	320..495	CDD:227455
		EFh	434..494	CDD:238008
		FRQ1	989..1135	CDD:227455
		EF-hand_11	1186..1286	CDD:286115
		EFh	1211..1264	CDD:298682
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148545
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930