DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC41C and Efcab6

DIOPT Version :9

Sequence 1:	NP_001246139.1	Gene:	TpnC41C / 35473	FlyBaseID:	FBgn0013348	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	XP_038936237.1	Gene:	Efcab6 / 315179	RGDID:	1309065	Length:	1509	Species:	Rattus norvegicus

Alignment Length:	181	Identity:	38/181 - (20%)
Similarity:	73/181 - (40%)	Gaps:	34/181 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ELTKEQTALLRNAFNAFDPEKNGYINTAMVGTILSMLGHQLDDATLADIIAEVDEDGSGQIEFEE 68
            ||.|.... :..|.:|.||.|.|||:...:..:|....::|...|...::.......:.::.:::
  Rat   316 ELVKSYEK-IEKALSAGDPSKGGYISLNYLKVVLDTFTYRLPRRTFIQLMRRFGLKTTTKVNWKQ 379

  Fly    69 FTTLA-----------------------ARFLVE-------EDAEAMMAELKEAFRLYDKEGNGY 103
            |.|..                       .||..|       :.:|.....||:|..:.....:|:
  Rat   380 FLTAVYERQGWEVSKTIPLKKRSSTEARNRFRKENIIKKLFKYSEERYTALKKALLIISPTPSGH 444

  Fly   104 ITTGVLREILRELDDKLTNDDLDMMIEEIDSDGSGTVDFDEFMEVMTGGDD 154
            :|...||.:|..:..||::.:.:.:.:..|.:|:|||.....::|:   ||
  Rat   445 VTWEDLRHVLNCVVVKLSDSEFNELKQTFDPEGTGTVKISSLLDVL---DD 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC41C	NP_001246139.1	PTZ00184	1..150	CDD:185504	36/175 (21%)
Efcab6	XP_038936237.1	FRQ1	82..264	CDD:227455
		EFh_parvalbumin_like	<420..490	CDD:330177	16/69 (23%)
		EF-hand motif	429..457	CDD:319994	8/27 (30%)
		EF-hand motif	465..490	CDD:319994	5/24 (21%)
		EFh_PI-PLC	869..980	CDD:333715
		EF-hand motif	869..897	CDD:320029
		EF-hand_7	873..927	CDD:404394
		EF-hand motif	904..929	CDD:320029
		FRQ1	1086..1247	CDD:227455
		EF-hand_11	1170..1274	CDD:401068
		PTZ00183	1335..1505	CDD:185503
		EF-hand_7	1447..1507	CDD:404394
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342444
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930