DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC41C and Calm3

DIOPT Version :9

Sequence 1:	NP_001246139.1	Gene:	TpnC41C / 35473	FlyBaseID:	FBgn0013348	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	NP_036650.1	Gene:	Calm3 / 24244	RGDID:	2259	Length:	149	Species:	Rattus norvegicus

Alignment Length:	150	Identity:	68/150 - (45%)
Similarity:	105/150 - (70%)	Gaps:	3/150 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDELTKEQTALLRNAFNAFDPEKNGYINTAMVGTILSMLGHQLDDATLADIIAEVDEDGSGQIE 65
            |:|:||:||.|..:.||:.||.:.:|.|.|..:||::..||....:|.|.|:|.|||.||:|.|:
  Rat     1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTID 65

  Fly    66 FEEFTTLAARFLVEEDAEAMMAELKEAFRLYDKEGNGYITTGVLREILRELDDKLTNDDLDMMIE 130
            |.||.|:.||.:.:.|:|   .|::||||::||:|||||:...||.::..|.:|||::::|.||.
  Rat    66 FPEFLTMMARKMKDTDSE---EEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIR 127

  Fly   131 EIDSDGSGTVDFDEFMEVMT 150
            |.|.||.|.|:::||:::||
  Rat   128 EADIDGDGQVNYEEFVQMMT 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC41C	NP_001246139.1	PTZ00184	1..150	CDD:185504	66/148 (45%)
Calm3	NP_036650.1	PTZ00184	1..149	CDD:185504	67/149 (45%)
Calm3	NP_036650.1	Necessary and sufficient for interaction with PCP4. /evidence=ECO:0000250\|UniProtKB:P0DP25	77..149		32/73 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23050
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010