DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TpnC41C and CALML6

DIOPT Version :9

Sequence 1:	NP_001246139.1	Gene:	TpnC41C / 35473	FlyBaseID:	FBgn0013348	Length:	154	Species:	Drosophila melanogaster
Sequence 2:	XP_005244786.2	Gene:	CALML6 / 163688	HGNCID:	24193	Length:	203	Species:	Homo sapiens

Alignment Length:	151	Identity:	52/151 - (34%)
Similarity:	83/151 - (54%)	Gaps:	2/151 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDELTKEQTALLRNAFNAFDPEKNGYINTAMVGTILSMLGHQLDDATLADIIAEVDEDGSGQIE 65
            |::.|:.||....:..|..||.|.||.:.|..:..::|:||.....:.||.:..:||.|..|...
Human    48 MTERLSAEQIKEYKGVFEMFDEEGNGEVKTGELEWLMSLLGINPTKSELASMAKDVDRDNKGFFN 112

  Fly    66 FEEFTTLAARFLVEEDAEAMMAELKEAFRLYDKEGNGYITTGVLREILRELDDKLTNDDLDMMIE 130
            .:.|  ||...:..|.|:...:||:.|||::||||.|||....|:.:|....:.|...:.:.|::
Human   113 CDGF--LALMGVYHEKAQNQESELRAAFRVFDKEGKGYIDWNTLKYVLMNAGEPLNEVEAEQMMK 175

  Fly   131 EIDSDGSGTVDFDEFMEVMTG 151
            |.|.||..|:|::||:.:|||
Human   176 EADKDGDRTIDYEEFVAMMTG 196

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TpnC41C	NP_001246139.1	PTZ00184	1..150	CDD:185504	49/148 (33%)
CALML6	XP_005244786.2	PTZ00184	48..195	CDD:185504	49/148 (33%)
		EFh	59..120	CDD:238008	19/62 (31%)
		EFh	133..195	CDD:238008	24/61 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001548
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23050
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.970