DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tif-IA and AT1G30590

DIOPT Version :9

Sequence 1:	NP_788084.1	Gene:	Tif-IA / 35454	FlyBaseID:	FBgn0032988	Length:	611	Species:	Drosophila melanogaster
Sequence 2:	NP_001320918.1	Gene:	AT1G30590 / 839939	AraportID:	AT1G30590	Length:	607	Species:	Arabidopsis thaliana

Alignment Length:	646	Identity:	157/646 - (24%)
Similarity:	271/646 - (41%)	Gaps:	138/646 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YTSKTDVTSILKTFSGVKRNQANAVAINKVRFSTPKEKGLAESVRVALEERNFHLVKEFTYFLRE 68
            ||....|.::.|..:.|:....:             :....::|....|:.:|..|.:....|:.
plant    21 YTDTDLVFAVRKALASVQNGDTD-------------DYSQLKTVMCLTEDADFDAVAQLETVLKS 72

  Fly    69 AELSDDEVVIIIKDAKRIVHNLTPEFVTVVEAL--LSLNWKKRSSEIIEAYTEFCIELMVTHNRY 131
            ..:|   |..|     .:||:     ..::||:  :||.:......:::|..:..|.|..|..:|
plant    73 LSVS---VAWI-----DLVHH-----KDLLEAIFKMSLWYHSHRPSVMDALVDLIISLAATSGKY 124

  Fly   132 LPIGVSKLIVHW----IPGDMDESDWVHGCPSEHVRNELKPIHKVLDRILTAVPMAFDIIIDAIS 192
            |...::.|:.::    ....:.::..|......|.|     :|..|.:|...:|:|...::..::
plant   125 LDPCLNMLVRNFSQPTFKHKVSQTQLVKKMQEVHPR-----VHAALHKISYLIPLAPWNLVSILA 184

  Fly   193 AKFPYF--KKPYHVTAGYLYNVLWLLEYKPIFE---ELVFQLVLQKLLLLDVNAPKDE-----IE 247
            ......  |.|..||  |:.|:| .||...|.|   .::..:|::::|.||:.:..|:     .:
plant   185 QNMRKIDKKDPSIVT--YVDNLL-RLENSSIGEVVGSVILMMVMERMLDLDLVSGCDDSNGGMFD 246

  Fly   248 LEMNDEEEKVEADTLFEIDDVCAENVPKSEKSVSHPVGKTLDVCLFLLYKFFDGKCRLNENSSEE 312
            :|:.|..|    .|:.|.|:. .....|...|..:.|.:.||..:.|.:...: .|:.::...|
plant   247 MELEDAVE----STMNEGDEF-PVGALKQNTSGGNVVSELLDKLMVLFFHHLE-SCQNSDRLDE- 304

  Fly   313 QRRTANRLFKMLLYLFDEVLLPSHNTHHVQFILFYATSL---------RSVYSEAFLDSLWTKVQ 368
                   :|::|...|:..:|.::.|...||::|||.||         .|...:.:|.|
plant   305 -------VFEILFKSFENYILNTYKTKFSQFLMFYACSLDPENCGVRFASKLLDIYLSS------ 356

  Fly   369 NPNVSAVIRHAAVGYMASFLSRARFLPLSTVTFYLKELTRWAHTYIDDSDAYKQNCS----LKAN 429
              |...:.|.:||.|:||:|||.:|||.|.|...||.|       :|:...|...|:    .:|:
plant   357 --NTCRLTRMSAVAYLASYLSRGKFLPASFVASMLKRL-------VDECAEYCGTCNDDVKPEAH 412

  Fly   430 LVFYSVCQAVFYLIAFRAKDLTASSKDLLFLQSLQ--LSRLAMCHLNPLRYCLAPVATAF----- 487
            .||||.|||:.|::.||.:.:....:.....:||:  ||.    .||||..||..|.:.|
plant   413 QVFYSGCQAILYVLCFRMRSIVEIPRFQSQFRSLESILSH----KLNPLLVCLPSVVSEFLKQAK 473

  Fly   488 AG----VTRTYQLAYCHTVLERNARRKLATVYGHEKCMPDETLESFFPFDPYVLKLSKKYIETNY 548
            ||    |:.::.....|       ..:|:..:|     ..|.|::||||||.:||:|..||..|:
plant   474 AGGLFIVSESFIFDDLH-------ESELSRAFG-----GFERLDTFFPFDPCLLKMSSSYISPNF 526

  Fly   549 MVYQSNDTDEYVYGSNKYGHSRKRGDSEMLEEDEFLIVDKRPKNFDLSKSQEFDKQFHFGS 609
            ..:....|   .||.:        ||.|:.:|   :||     |.|...::|.|......|
plant   527 NFWSMVKT---TYGED--------GDEELCDE---VIV-----NGDADSAEEPDDDVELDS 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tif-IA	NP_788084.1	RRN3	40..553	CDD:283082	138/552 (25%)
AT1G30590	NP_001320918.1	RRN3	30..534	CDD:368388	140/582 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	124	1.000	Domainoid score	I1809
eggNOG	1	0.900	-	-		E1_KOG2434
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39531
Inparanoid	1	1.050	126	1.000	Inparanoid score	I1929
OMA	1	1.010	-	-		QHG55528
OrthoDB	1	1.010	-	-		D855834at2759
OrthoFinder	1	1.000	-	-		FOG0002748
OrthoInspector	1	1.000	-	-		otm3288
orthoMCL	1	0.900	-	-		OOG6_102817
Panther	1	1.100	-	-	O	PTHR12790
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2132
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840