Protein Alignment Tif-IA and rrn3

DIOPT Version :9

• Sequence 1: NP_788084.1
• Gene: Tif-IA / 35454
• FlyBaseID: FBgn0032988
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: XP_005164166.1
• Gene: rrn3 / 558718
• ZFINID: ZDB-GENE-080225-1
• Length: 612
• Species: Danio rerio
• Alignment Length: 604
• Identity: 196/604 - (32%)
• Similarity: 312/604 - (51%)
• Gaps: 49/604 - (8%)

  Fly    22 RNQANAVAINKVRFSTPKEKGLAESVRVALEERNFHLVKEFTYFLREAELSDDEVVIIIKDAKRI 86
            |:..|...:..|||.......||:..:.  :..::.|:|   :.|.:.::.|.:::..:::.:..
Zfish     6 RDFINTPPLKTVRFGGTVANTLAKLQKG--DTSDYELIK---HQLSDPDIKDAQIINWLQEFRTC 65

  Fly    87 VHNLTPEFVTVVEALLSLNWKKRSSEIIEAYTEFCIELMVTHNRYLPIGVSKLIVHWIP------ 145
            |..|..:...:|..:|.|.|..||..::|.|..|...|:.....||...:..::.::.|
Zfish    66 VTQLGKDHEQLVYVVLKLPWLGRSQAVVEEYLAFLSNLVSAQTVYLRACLRMVVTNFSPKRIRIQ 130

  Fly   146 -GDMDESDWVHGCPSEHVRNELKPIHKVLDRILTAVPMAFDIIIDAISAKFPYFKKPYHVTAGYL 209
             |::|.||  .....|::.......|:.|..|...||.....::..::.|||:.:|.......|:
Zfish   131 EGNVDISD--SDDEDENLPRTFDNCHQALQLIARYVPSTSRFLMPILTDKFPFVQKSSRTLECYV 193

  Fly   210 YNVLWLLEYKPIFEELVFQLVLQKLLLLDVNAPKDEI-ELEMNDEEEKVEA---DTLFEIDDVCA 270
            :|:|.:..|.|...:.|.:|::.|:|:|||:||:.|| |:|...::....|   |.||.:|:  .
Zfish   194 HNLLRVTVYIPDLRKDVLELIISKMLMLDVSAPRSEIEEVESGAQQGASGASQDDCLFNMDE--E 256

  Fly   271 ENVPKSE----KSVSHPVGKTLDVCLFLLYKFFDGKCRLNENSSEEQRRTANRLFKMLLYLFDEV 331
            |:.|.|.    .::.|||.:.||..:.:|..:......:|.....|:.:.   |::.|:.:||:|
Zfish   257 EDSPLSSGADGGAMVHPVAERLDTMMTVLLAYIKDVSHVNGTLDIEKTKA---LYRDLVSVFDKV 318

  Fly   332 LLPSHNTHHVQFILFYATSLRSVYSEAFLDSLWTKVQNPNVSAVIRHAAVGYMASFLSRARFLPL 396
            :||:|.:.||||.:||..|.|...:|||||.||..:|.||..:|:|.:|.|||.||::||:|||:
Zfish   319 VLPTHASCHVQFYMFYLCSFRLGLAEAFLDHLWKLLQGPNQPSVLRQSAAGYMGSFMARAKFLPV 383

  Fly   397 STVTFYLKELTRWAHTYIDDSDA-YKQNCSLKANLVFYSVCQAVFYLIAFRAKDLTASS--KDLL 458
            |||...|..|..|.|.|||..|: .|..|.:..:..||:.||||||.:.|:...:...:  |.|.
Zfish   384 STVKACLDLLVPWLHLYIDSQDSGSKAFCDINLHGPFYTACQAVFYTLIFKHNAILEGNMKKGLA 448

  Fly   459 FLQSLQLSRLAMCHLNPLRYCLAPVATAFAGVTRTYQLAYCHTVLERNARRKL----ATVYGHEK 519
            :||.|.|.|:.||.|||||.||..|...||.:||.|||.:|:|::|||.|..|    ::|.|...
Zfish   449 YLQGLNLERIVMCQLNPLRVCLPAVTNMFAAITRKYQLVFCYTIIERNNRHLLPVVRSSVGGSSV 513

  Fly   520 CMPDETLESFFPFDPYVLKLSKKYIETNYMVYQSNDTDEYVYGSNKYGHSRKRGDSEMLEEDEFL 584
            ......|:||||||||:||.|.|.||..|.|::  :..:.:.|..|    ::.....|.|||:||
Zfish   514 ATNTNPLDSFFPFDPYLLKSSGKLIEPIYQVWE--EPSDCMIGVPK----KEIPKGSMEEEDDFL 572

  Fly   585 ---------IVDKRPKNFD 594
                     ||...|.:::
Zfish   573 HGETPHGDSIVGMTPGSYE 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tif-IA	NP_788084.1	RRN3	40..553	CDD:283082	180/534 (34%)
rrn3	XP_005164166.1	RRN3	23..547	CDD:283082	180/537 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587094
Domainoid	1	1.000	289	1.000	Domainoid score	I1523
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39531
Inparanoid	1	1.050	293	1.000	Inparanoid score	I2761
OMA	1	1.010	-	-		QHG55528
OrthoDB	1	1.010	-	-		D208219at33208
OrthoFinder	1	1.000	-	-		FOG0002748
OrthoInspector	1	1.000	-	-		oto40706
orthoMCL	1	0.900	-	-		OOG6_102817
Panther	1	1.100	-	-	LDO	PTHR12790
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2132
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910