Protein Alignment Tif-IA and Rrn3

DIOPT Version :9

• Sequence 1: NP_788084.1
• Gene: Tif-IA / 35454
• FlyBaseID: FBgn0032988
• Length: 611
• Species: Drosophila melanogaster
• Sequence 2: NP_001129318.1
• Gene: Rrn3 / 304714
• RGDID: 1305001
• Length: 661
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 199/663 - (30%)
• Similarity: 320/663 - (48%)
• Gaps: 105/663 - (15%)

  Fly    16 TFSGVKRNQANAVAINKVRFSTPKEK-----GLAESVRVAL---EERNFHLVKEFTYFLREAELS 72
            |.|..:...:|.:|:....||:|..|     |....|.:..   |..:..|:|.   .|.:.::.
  Rat    21 TLSASRTGLSNMLALESDFFSSPPRKTVRFGGTVTDVLLKYKKGETNDLELLKN---QLSDPDIK 82

  Fly    73 DDEVVIIIKDAKRIVHNLTPEFVTVVEALLSLNWKKRSSEIIEAYTEFCIELMVTHNRYLPIGVS 137
            ||:::..:.:.:..|..||.:|..::..:|.|.|..||..::|.|..|...|:.....:|...:|
  Rat    83 DDQIINWLLEFRSSVMYLTKDFEQLINIILRLPWLNRSQTVVEEYLAFLGNLVSAQTVFLRPCLS 147

  Fly   138 KLIVHWIP-------GDMDESDWVHGCPSEHVRNEL----KPIHKVLDRILTAVPMAFDIIIDAI 191
            .:..|::|       |.:|.|:      ||...:.|    ...||.|..|...||.....::..:
  Rat   148 MIASHFVPPRVIVKEGGIDVSE------SEDEDDNLPANFDTCHKALQIITRYVPSTPWFLMPIL 206

  Fly   192 SAKFPYFKKPYHVTAGYLYNVLWLLEYKPIFEELVFQLVLQKLLLLDVNAPKDEIELEMNDEEEK 256
            ..|||:.:|.......|::|:|.:..|.|.....:.:|:::|.|.|||:..:.:|     |:.|:
  Rat   207 VEKFPFVRKSERTLECYVHNLLRISLYFPTLRREILELIIEKSLKLDVSVSRQDI-----DDAEE 266

  Fly   257 VEADT---------LFEID-DVCAENVPKSEKS----VSHPVGKTLDVCLFLLYKFFDGKC---- 303
            ..|.|         ||.:| |...:...|:|:.    ::||..:.||:.|.||..:.|..|
  Rat   267 TAAQTYGGTDAAEGLFNMDEDEETDPEKKAEQERPGRMAHPTAERLDILLSLLLSYIDDVCHVQG 331

  Fly   304 RLNENSSEEQRRTANRLFKMLLYLFDEVLLPSHNTHHVQFILFYATS-----LRSVYSEAFLDSL 363
            :::.|.:::       |::.|:.:||:::||:|.:.||||.:|:..|     |...::||||:.|
  Rat   332 KIDNNKTKD-------LYRDLISIFDKLVLPTHASCHVQFFMFFLCSFKLSLLLQGFAEAFLEHL 389

  Fly   364 WTKVQNPNVSAVIRHAAVGYMASFLSRARFLPLSTVTFYLKELTRWAHTYIDDSDA-YKQNCSLK 427
            |.|:|:||...:||.||..|:.|||:||:|:||.||...|..|..|.|.|::..|: .|..|.:.
  Rat   390 WKKLQDPNNPVIIRQAAANYIGSFLARAKFIPLITVKSCLDLLVNWLHLYLNSQDSGTKAFCDVA 454

  Fly   428 ANLVFYSVCQAVFYLIAFRAKDLTASS--KDLLFLQSLQLSRLAMCHLNPLRYCLAPVATAFAGV 490
            .:..|||.||||||.:.||.|.|.:.:  :.|.:||||...|:.:..||||:.||..|...||.:
  Rat   455 LHGPFYSACQAVFYTVVFRHKQLLSGNLKEGLRYLQSLNFERIVLSQLNPLKICLPRVVNFFAAI 519

  Fly   491 TRTYQLAYCHTVLERNARRKL----ATVYGHEKCMPDETLESFFPFDPYVLKLSKKYIETNYMVY 551
            |..|||.:|:|::|||.|:.|    :|..|.........|::||||||.:||.|||:|:..|..:
  Rat   520 TNKYQLVFCYTIMERNNRQMLPVIRSTAGGDSVQTCTNPLDTFFPFDPCMLKRSKKFIDPVYQAW 584

  Fly   552 QSNDTDEYVYGSNKYGHSRKRGDSEML--EEDEFL---------IVDKRPKNFDLSKSQEFDKQF 605
            :....:|       ....||....|::  |:|:||         :....|.:||.
  Rat   585 EDMSDEE-------LQELRKPTRKELVEDEDDDFLKGEVPQSDTVAGLTPNSFDT---------- 632

  Fly   606 HF-------GSSP 611
            ||       ||.|
  Rat   633 HFRSPSSSVGSPP 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tif-IA	NP_788084.1	RRN3	40..553	CDD:283082	176/561 (31%)
Rrn3	NP_001129318.1	RRN3	54..588	CDD:283082	174/554 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346133
Domainoid	1	1.000	269	1.000	Domainoid score	I1776
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H39531
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2887
OMA	1	1.010	-	-		QHG55528
OrthoDB	1	1.010	-	-		D208219at33208
OrthoFinder	1	1.000	-	-		FOG0002748
OrthoInspector	1	1.000	-	-		oto98129
orthoMCL	1	0.900	-	-		OOG6_102817
Panther	1	1.100	-	-	LDO	PTHR12790
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2132
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.910