DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3262 and NUBPL

DIOPT Version :9

Sequence 1:	NP_001260688.1	Gene:	CG3262 / 35452	FlyBaseID:	FBgn0032986	Length:	293	Species:	Drosophila melanogaster
Sequence 2:	NP_079428.2	Gene:	NUBPL / 80224	HGNCID:	20278	Length:	319	Species:	Homo sapiens

Alignment Length:	266	Identity:	118/266 - (44%)
Similarity:	173/266 - (65%)	Gaps:	7/266 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QVKLMARGLPKKQPIIGVQDIIVVASGKGGVGKSTVAVNFACSLA--KLGKRVGLLDGDIFGPTI 83
            :.::|:|||||::||.||:.:||||||||||||||.|||.|.:||  ...|.:||||.|::||::
Human    49 RTQIMSRGLPKQKPIEGVKQVIVVASGKGGVGKSTTAVNLALALAANDSSKAIGLLDVDVYGPSV 113

  Fly    84 PLLMNVHGEPVVNDKNLMIPPQNYNVKCLSMGMLTPVETSVIWRGPLVMSAIQRLLKGTDWGLLD 148
            |.:||:.|.|.::..|||.|..||.:.|:|||.|......|:|||.:|||||::||:..|||.||
Human   114 PKMMNLKGNPELSQSNLMRPLLNYGIACMSMGFLVEESEPVVWRGLMVMSAIEKLLRQVDWGQLD 178

  Fly   149 VLVIDTPPGTGDVHLSLSQHAPITGVILVTTPHTAAVQVTLKGASMYEKLNVPIFGVVENMKYTI 213
            .||:|.|||||||.||:||:.||||.::|:||...|:....|||.|:.:::||:.|:|:||....
Human   179 YLVVDMPPGTGDVQLSVSQNIPITGAVIVSTPQDIALMDAHKGAEMFRRVHVPVLGLVQNMSVFQ 243

  Fly   214 CQNCNQRLEFFKDSRISSLPRK-----LISLPLDSRIADSNESGVPVVIKYPDSKYSYLFTQLAE 273
            |..|..:...|.......|.:.     |..:||...|.:::::|.|:|...|:|..:..:.::|.
Human   244 CPKCKHKTHIFGADGARKLAQTLGLEVLGDIPLHLNIREASDTGQPIVFSQPESDEAKAYLRIAV 308

  Fly   274 EITQIL 279
            |:.:.|
Human   309 EVVRRL 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3262	NP_001260688.1	ParA	37..275	CDD:287566	108/244 (44%)
CG3262	NP_001260688.1	minD_arch	41..281	CDD:131024	108/246 (44%)
NUBPL	NP_079428.2	ParA	65..311	CDD:287566	109/245 (44%)
NUBPL	NP_079428.2	minD_arch	69..311	CDD:131024	107/241 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151441
Domainoid	1	1.000	217	1.000	Domainoid score	I2689
eggNOG	1	0.900	-	-		E1_COG0489
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11854
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3377
Isobase	1	0.950	-	0	Normalized mean entropy	S1527
OMA	1	1.010	-	-		QHG53899
OrthoDB	1	1.010	-	-		D1166096at2759
OrthoFinder	1	1.000	-	-		FOG0005727
OrthoInspector	1	1.000	-	-		oto89333
orthoMCL	1	0.900	-	-		OOG6_100169
Panther	1	1.100	-	-	LDO	PTHR42961
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5312
SonicParanoid	1	1.000	-	-		X4124
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750