Protein Alignment Ir40a and Ir75b

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001137966.2
• Gene: Ir75b / 8673994
• FlyBaseID: FBgn0261402
• Length: 605
• Species: Drosophila melanogaster
• Alignment Length: 721
• Identity: 146/721 - (20%)
• Similarity: 259/721 - (35%)
• Gaps: 209/721 - (28%)

  Fly    46 SSLAILALPSLALSDGVCQKERNVYLDDFLQRLHRSNYKSVVFSQTELFFQHIEENLQGANECIS 110
            |.||:||            :.:|::..  .|.||         |..:|....:..|:......:.
  Fly    29 SHLALLA------------QSKNIFTQ--FQPLH---------SDIQLNDDFLNHNILKLGVFLD 70

  Fly   111 LILDEPNQLLN-SLHDRHLGHRLSLFIFYWGARWPPSSRVIRFRE-----PLRVVVVTR-PRKKA 168
            :..|:...:|: :...|...||....|:.....:  |.....|:|     ...|..||. |..|.
  Fly    71 INCDKSGTVLDMASAKRFFSHRYHWLIYDRSMNF--SVLESHFKEAQIFVDADVTYVTHDPFSKN 133

  Fly   169 FRIY--YNQARP-------CSDSQLQLVNWYDGDNLGLQR-IPLLPT--ALSVYANFKGRTFRVP 221
            |.:|  ||:.|.       .:|.::    :.:..|..::| :..|.|  ||....:|.|.|.|..
  Fly   134 FLLYDVYNKGRQLGGELNITADREI----FCNKTNCRVERYLSELYTRSALQHRKSFTGLTMRAT 194

  Fly   222 VFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRT 286
            ..       ||....:....|.|:.::|..:.::.......::....|...::.:||||...
  Fly   195 AV-------VTALPLNVSIKEIFDFMNSKYRIQLDTYARLGYQARQPLRDMLDCKFKYIFRD--- 249

  Fly   287 QGSMRSEDGKDSNDSFTGG-IGLLQSGQADFFLGDVGLSWER----RKAIEFSFFTLADSGAFAT 346
                |..||     :.||| ||.|...:||..:.....|::|    :...:||.|  .:...|..
  Fly   250 ----RWSDG-----NATGGMIGDLILDKADLAIAPFIYSFDRALFLQPITKFSVF--REICMFRN 303

  Fly   347 HAPRRLNEALA---IMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIWRRRWANSDVEHLGELYI 408
              ||.::..|:   .::||...:|....|.::.:|.:.:    :.:|..||
  Fly   304 --PRSVSAGLSATEFLQPFSGGVWLTFALLLLLAGCLLW----VTFILERR-------------- 348

  Fly   409 HMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCI---WFTLRLFLKQSCNELHNGYRAKFLTIV 470
                 |:..|.||   ...:||       ....||   |.|.|..          |.|..|..:
  Fly   349 -----KQWKPSLL---TSCLLS-------FGAGCIQGAWLTPRSM----------GGRMAFFAL- 387

  Fly   471 YWIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGY------RLYVE-KESSSLEM 528
              :..:|::.:.|::.:.|:......:..|.|||:|..:.:..|.      |:||| .|...:
  Fly   388 --MVTSYLMYNYYTSIVVSKLLGQPIKSNIRTLQQLADSNLDVGIEPTVYTRIYVETSEEPDV-- 448

  Fly   529 LENGTELFRQLYALMRQQVI---NDPQGFFIDSVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYG 590
                    |.||   |::|:   ..|...:|.: |||:..:.:
  Fly   449 --------RDLY---RKKVLGSKRSPDKIWIPT-EAGVLSVRD---------------------- 479

  Fly   591 SNNFQLSQKLYTRYSAVAVQIGCPFLGS--LNNVLMQLFESGILD-KMTAAEYAKQ--YQE---V 647
                   |:.:...:.||.  |..|:..  |.:.:.:|.|..:.| ..|....||:  |.|   :
  Fly   480 -------QEGFVYITGVAT--GYEFVRKHFLAHQICELNEIPLRDASHTHTVLAKRSPYAELIKL 535

  Fly   648 EATRIYKGSVQAKNSEAYSRTE----SYDSTV------ISPLNLRMLQGAFIALGVGSLAAGVIL 702
            ...|:.:..|..|:..::..|:    .::.||      .:||.:.:|....:.:|        ||
  Fly   536 SELRMLETGVHFKHERSWMETKLHCYQHNHTVAVGLEYAAPLFIILLGAIILCMG--------IL 592

  Fly   703 LLEIVF 708
            .||:::
  Fly   593 GLEVIW 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	20/75 (27%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	22/101 (22%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	30/153 (20%)
Ir75b	NP_001137966.2	Lig_chan-Glu_bd	<235..283	CDD:463166	17/59 (29%)
		Periplasmic_Binding_Protein_Type_2	<259..>325	CDD:473866	17/69 (25%)
		Lig_chan	343..584	CDD:459656	64/327 (20%)