DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir40a and Ir94d

DIOPT Version :9

Sequence 1:	NP_610140.4	Gene:	Ir40a / 35449	FlyBaseID:	FBgn0259683	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_001138099.1	Gene:	Ir94d / 7354412	FlyBaseID:	FBgn0259193	Length:	593	Species:	Drosophila melanogaster

Alignment Length:	487	Identity:	90/487 - (18%)
Similarity:	154/487 - (31%)	Gaps:	176/487 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 RRLNEALAIMRPFKQDIW------------PHLIL------TIIFSGPI----------FYGIIA 386
            |||:.:..|.....:::.            |.||:      .:|||||:          :...:.
  Fly   162 RRLDNSTVIFEKRLENLHGYEVPIALGGSSPRLIVYRDLEGKLIFSGPVGNFMKSFEQRYNCRLV 226

  Fly   387 LPY------IWRRRWANSDVEH------LGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPH-QL 438
            .||      |...|...:.|::      ||.:|..:.|.....|..|......:....::|| ||
  Fly   227 QPYPFDESAISPARDLIASVQNGSVQIALGAIYPQVPYTGYSYPIELMSWCLMMPVPEEVPHSQL 291

  Fly   439 FQK---------------CIWFTLRLFLKQSCNELHNGYRAKFLTIVYWIAATYVLAD-VYSAQL 487
            :..               .|..||.:.|:     || |||..|        :.|.|.| .....|
  Fly   292 YSMVFSPMAFGITIVAMVLISLTLSMALR-----LH-GYRVSF--------SEYFLHDSCLRGVL 342

  Fly   488 TSQFARPAREPPINTLQRLQAAMIHDGYRLYVEKESSSLEMLENGTELFRQLYALMRQQVINDPQ 552
            :..|....|.|.:.....|...::  |..:               |..:...::.........||
  Fly   343 SQSFYEVLRAPALIKAMYLVICLL--GLLI---------------TSWYNSYFSTFVTSAPRFPQ 390

  Fly   553 GFFIDSV-EAGIKLIAEGGEDKAVLGGRETLFF--NVQQYGSNNFQLSQ----------KLYTRY 604
            ....:|: .:.||::....|.:.:      |||  |:::| |:.|||.:          ...|||
  Fly   391 LTSYESIRHSNIKIVIWKPEYEML------LFFSENMEKY-SSIFQLQEDYKEFLHLRDSFDTRY 448

  Fly   605 SAV-------------------------------AVQIGCPFLGSLNNVLMQLFESGILDKMTAA 638
            ..:                               .|.|..|.:  .|::..:.|:..||| :||.
  Fly   449 GYMMPMEKWSLMKEQQRVFSSPLFSLQDDLCVFHTVPIVFPMV--KNSIFKEPFDRLILD-VTAT 510

  Fly   639 EYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSL------- 696
            ....:::::..|.:.|..........:.:                   .|.|:.||.|
  Fly   511 GLLSRWRDMSFTEMIKAGQLGLEDRGHPK-------------------EFRAMKVGDLIQIWRFV 556

  Fly   697 -----AAGVILLLEIVFI---KLDQARLWMLC 720
                 .|.::.|||::..   |:.|...:|.|
  Fly   557 GWMLGLATIVFLLELICFWRHKMWQNMKYMFC 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	PBP2_LTTR_substrate	216..338	CDD:330233
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:328725	14/74 (19%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:328725	31/184 (17%)
Ir94d	NP_001138099.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463011
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42643
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030