Protein Alignment Ir40a and grin2ab

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_073805448.1
• Gene: grin2ab / 570493
• ZFINID: ZDB-GENE-070424-223
• Length: 1445
• Species: Danio rerio
• Alignment Length: 885
• Identity: 161/885 - (18%)
• Similarity: 276/885 - (31%)
• Gaps: 331/885 - (37%)

  Fly    13 LLGLLNSTRLTFIGNDESDTAIALTQIVRGLQQSSLAILA------------------------- 52
            :||:...:.:|..   |.|::.:..|....|||.:|.:||
Zfish   113 ILGIHGGSAMTMA---EKDSSSSFFQFGASLQQEALLMLAIMEEYDWHVFSVVTTKFPGFQEFIA 174

  Fly    53 --------------LPSLALSDGVCQKERNVYLDDFLQRLHRSNYKSVVFSQTELFFQHIEENLQ 103
                          |.|:...|||.:.|...::.  |:|:.         |...|.:...:|
Zfish   175 TVRVTVDHSFVRWDLQSVVTLDGVGEPEDRAHVQ--LKRIQ---------SPVILLYCSKDE--- 225

  Fly   104 GANECISLILDEPNQL----------LNSLHDRHLGH--------RLSLFIFYWGARWPPSSRV- 149
                 .:|:::|...|          :.||...:|.|        .:|:....|.  :|..:|:
Zfish   226 -----AALVMEEARSLGLTGAGFVWIVPSLTTGNLEHIPEAFPAGMISVTYDEWD--YPLETRLQ 283

  Fly   150 -----------IRFREPLRVVVVTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGDNLGLQRIPLL 203
                       ..|||..|:...|..       .|.|:.........|..:..|.|||.:....:
Zfish   284 DAVGIISSAAAAMFREEGRIPDGTAS-------CYGQSEKPEVPPSALRRYMMGVNLGGKDHSFM 341

  Fly   204 -------PTALSVYANFK------GR------TFRVPVFHSPPWFWVTYCNNSF---EEDEEFNS 246
                   |..:.:..|.:      ||      ..:.||       |..|  |||   :.||...|
Zfish   342 DDGYQVNPKLVVIVLNTEREWEKMGRWENHSLRLKFPV-------WPRY--NSFGDMDADENHLS 397

  Fly   247 LDSIEKRKVRV-------TGG--------RDH--------------------RLLMLLSKHMNFR 276
            :.::|:|...:       ||.        |.|                    .:|..:::::.|.
Zfish   398 IVTLEERPFVIVDDVDILTGTCMRNSVPCRKHIKDNTTEGSYVKKCCKGFCIDILKKIARNVKFT 462

  Fly   277 FK-YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFSF----- 335
            :. |:...|:        .||..|:.:.|.:|.:...:|...:|.:.::.||.:||:||.
Zfish   463 YDLYLVTNGK--------HGKKINNVWNGMVGEVVYKKAVMAVGSLTINEERSEAIDFSVPFVET 519

  Fly   336 -FTLADSGAFATHAPRRLNEALAIMRPFKQDIW--PHLILTIIFSGPIFYGIIALPYIWRRRWAN 397
             .::..|.:..|.:|.      |.:.||...:|  ..::|.|:.:..:|......|..:.|..|.
Zfish   520 GISVMVSRSNGTVSPS------AFLEPFSASVWVMMFVMLLIVTAIAVFLFEFISPLGFNRNLAQ 578

  Fly   398 SDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCNELHN-- 460
            ....|                               .|.....|.:|....|....|. .:.|
Zfish   579 GKDPH-------------------------------GPSFTIGKAVWLLWGLVFNNSV-PVQNPR 611

  Fly   461 GYRAKFLTIVYWIAATYVLADVYSAQLTS-----------------QFARP-AREPPINTLQRLQ 507
            |..:||:..|:...|...||. |:|.|.:                 :|..| :..||..
Zfish   612 GTTSKFIVSVWAFFAVIFLAS-YTANLAAFMIQEEFVDQVTGLSDRKFQSPYSYSPPFR------ 669

  Fly   508 AAMIHDGYRLYVEKESSSLEMLENG-TEL-FRQLYALMRQQVINDPQGFFIDSV----------- 559
                              ...:.|| ||. .|:.|..|.|.::...|...:|::
Zfish   670 ------------------FGTVPNGSTERNIRKNYPAMHQYMVKYHQTGVVDALVSLKTGKLDAF 716

  Fly   560 --EAGIKLIAEGGED--KAVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLN 620
              :|.:.....|.:|  |.|..|...:|... .||                :|:|.|..:...::
Zfish   717 IYDAAVLNYMAGRDDGCKLVTIGSGYIFATT-GYG----------------IAMQKGSYWKRLVD 764

  Fly   621 NVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQ 685
            ..::.:...|            :.:|:||..: .|....:.:|..|          |.|::..:.
Zfish   765 LAILGIIGDG------------EMEELEAQWL-TGICHNEKNEVMS----------SQLDVDNMA 806

  Fly   686 GAFIALGVGSLAAGVILLLEIVFIKLDQARLWM----LCS 721
            |.|..|.    ||..:.|:..|:..|...||..    |||
Zfish   807 GVFYMLA----AAMALSLITFVWEHLFYWRLRYCFTGLCS 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	17/77 (22%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	22/101 (22%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	25/157 (16%)
grin2ab	XP_073805448.1	None