Protein Alignment Ir40a and grin3ba

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_021323058.1
• Gene: grin3ba / 566411
• ZFINID: ZDB-GENE-070912-354
• Length: 1118
• Species: Danio rerio
• Alignment Length: 843
• Identity: 174/843 - (20%)
• Similarity: 277/843 - (32%)
• Gaps: 274/843 - (32%)

  Fly     9 LLPYLLGLLNS---TRLTFIGNDESDTAIAL------------TQIVRG--LQQSSLAILALPSL 56
            ||..||....|   :.:...|:|...||..|            ...:.|  |...||..:..|..
Zfish   236 LLSQLLSRTPSAPASSVVLFGSDPECTATVLHCAHQLSGTLPPMHWIMGYPLSLDSLHSIGSPLG 300

  Fly    57 ALSDG-VCQKERNVYLDDFLQRLHRSNYKSVVFSQTELFFQHIEENLQGANECISLILDEPNQLL 120
            .::.| |.:|..|.|:.|.||.:.|:.|.:.:........|::.       .|    .|:||:
Zfish   301 LMAYGEVNRKPLNFYIRDTLQLIGRAVYAATMVRPDLALIQNMV-------NC----FDKPNK-- 352

  Fly   121 NSLHDRHLGHRLSLFIFYWGARWPPSSRVIRFREPLRVV-----VVTRPRKKAFRIYYNQARPCS 180
                     |.|.....|. ||:..::.......|:||.     |:|..|   |.|:..|..|..
Zfish   353 ---------HELPSSGQYL-ARFLSNTSFTGLTGPVRVERSFSRVLTSQR---FHIWSLQRDPLG 404

  Fly   181 D-SQLQLVNWYDG----DNLGL-------QR-----IPL-------LPTALSVYANFKGRTFRVP 221
            . |.:.:.:|..|    :..||       ||     |.|       ||.|        |...||.
Zfish   405 QPSWVTVASWQSGRLELEEQGLWPGVTQHQREDGPGIRLGGRWQAGLPVA--------GSRLRVV 461

  Fly   222 VFHSPPWFWV------------TYC-----NNS------FEEDEEFNSLDSIEKRKVRVTGGRDH 263
            .....|:.:.            ..|     |||      |.|.|:.|| .|:.....:...|...
Zfish   462 TLVEHPFVFTREVDEEGQCPAGQLCLDPQTNNSEVLNQLFRELEQTNS-SSLPTDMRKCCYGYCI 525

  Fly   264 RLLMLLSKHMNFRFK-YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWER 327
            .||..|::.|:|.|. ||...|:.        |......::|.:|.|.||.||..:....::..|
Zfish   526 DLLEKLAEDMHFEFDLYIVGDGKY--------GAWKGGRWSGLVGDLLSGVADMAVTSFSINSAR 582

  Fly   328 RKAIEFS--FF------------TLADSGAFATHAPRRLNEALAIMRPFKQDIWPHLILTIIFSG 378
            .:.|:|:  ||            |.|..|||              |.|....:|..:.:.:
Zfish   583 SRVIDFTSPFFSTSLGILVRSKDTAAPIGAF--------------MWPLHWSMWVGIFVAL---- 629

  Fly   379 PIFYGIIALPYIWRRRWANSD---VEHLGELYIHM-TYLKEITPRLLKLKPRTVLSAHQMPHQLF 439
                .|.|| :|....| ||.   ..| |...|.: :|...:......|..|||  |.:.|
Zfish   630 ----HITAL-FITLYEW-NSPFGMTPH-GRNRIRVFSYSSALNLCYAILFGRTV--ASKTP---- 681

  Fly   440 QKCIWFTLRLFLKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPINTLQ 504
             ||                   :..:||..::.|....||:. |:|.|.:.....      .|.:
Zfish   682 -KC-------------------WTGRFLMNLWAIFCLLVLSS-YTANLAAVMVGE------KTFE 719

  Fly   505 RLQAAMIHD--------GYRLYVEKESSSLEMLENGTELFRQLYALMRQ-----------QVIND 550
            .:..  |||        |:|....:|||:.:.::..   |.:::..||:           .:..|
Zfish   720 EVSG--IHDVKLHHPSLGFRFGTVRESSAEDYVKKS---FPEMHEYMRRFNKPTTPDGVSTLKTD 779

  Fly   551 P---QGFFID--------SVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRY 604
            |   ..|.:|        |::|..||:..|..            |.::.||
Zfish   780 PPQLDAFIMDKALLDYEVSIDADCKLLTVGKP------------FAIEGYG-------------- 818

  Fly   605 SAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTE 669
              :.:....|...:::..:.:....|.:|.:    :.|.|:.|..           ....::.||
Zfish   819 --IGLPQNSPLTRNVSEYVSRYKSDGYMDML----HDKWYKVVPC-----------GKRVFAVTE 866

  Fly   670 SYDSTVISPLNLRMLQGAFIALGVGSLAAGVILLLEIVFIKLDQARLWMLCSRLQWIRYDRKV 732
            :..      :.::...|.|:.|.||...|.:.||.|..|.:.....|........|:...:|:
Zfish   867 TLQ------MGIQHFSGLFVLLCVGVAGALLTLLGEHAFFRFILPHLRHQQRFKYWLHTSQKI 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	20/73 (27%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	23/107 (21%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	27/170 (16%)
grin3ba	XP_021323058.1	Periplasmic_Binding_Protein_type1	36..427	CDD:471960	49/216 (23%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	99/498 (20%)
		Lig_chan	618..885	CDD:459656	63/364 (17%)