DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir40a and grik1b

DIOPT Version :9

Sequence 1:NP_610140.4 Gene:Ir40a / 35449 FlyBaseID:FBgn0259683 Length:732 Species:Drosophila melanogaster
Sequence 2:XP_690040.5 Gene:grik1b / 561540 ZFINID:ZDB-GENE-070821-1 Length:906 Species:Danio rerio


Alignment Length:525 Identity:96/525 - (18%)
Similarity:192/525 - (36%) Gaps:117/525 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   219 RVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTG-----------------GRDH--- 263
            ::.|::|.....:|..|    :|:..|..||:..|.:.||.                 |.|.   
Zfish   442 KIGVWNSNTGLNLTDSN----KDKNTNVTDSMANRTLIVTTILENPYVMYKKSDKPLYGNDRFEG 502

  Fly   264 ---RLLMLLSKHMNFRFKYIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSW 325
               .||..||..:.|.:   |....|.|...:::.|   ..:.|.:..|....||..:..:.:::
Zfish   503 YCLDLLKELSNILGFSY---EVKLVTDGKYGAQNDK---GEWNGMVRELIDHVADLAVAPLTITY 561

  Fly   326 ERRKAIEFS--FFTLADSGAFATHAPRRLNEAL-AIMRPFKQDIWPHLILTIIFSGPIFYGIIA- 386
            .|.|.|:||  |.||..|..:  |.|...|..: :.:.|...|||.:::|..:....:.: :|| 
Zfish   562 VREKVIDFSKPFMTLGISILY--HKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLF-VIAR 623

  Fly   387 -LPYIW-RRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRL 449
             .||.| .....|.|.:.:...:                   |::::           :||.:..
Zfish   624 FTPYEWYNPHPCNPDSDVVENNF-------------------TLINS-----------VWFGVGA 658

  Fly   450 FLKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPINTLQ------RLQA 508
            .::|....:......:.:..::|. .|.::...|:|.|.:.......:.||::..      :::.
Zfish   659 LMQQGSELMPKALSTRIVGGIWWF-FTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTKIEY 722

  Fly   509 AMIHDGYRLYVEKESSSLEMLENGTELFRQLYALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDK 573
            ..:.||..:...|:|.        ...:.:::|.|..:    .....:.:...||:.:..  .|.
Zfish   723 GAVRDGSTMTFFKKSK--------ISTYEKMWAFMSSR----KNTALVKNNREGIQRVLT--TDY 773

  Fly   574 AVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAA 638
            |:|....::.: :.|...|..|:...:.::...|...||.|:...:...::||.|.|.|..|   
Zfish   774 ALLMESTSIEY-ISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMM--- 834

  Fly   639 EYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLAAGVILL 703
                      ..:.::|          :.....||...|.|.:..:.|.||.|..|.:.:..:.:
Zfish   835 ----------KEKWWRG----------NGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAI 879

  Fly   704 LEIVF 708
            .|.::
Zfish   880 GEFIY 884

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir40aNP_610140.4 PBP2_LTTR_substrate 216..338 CDD:330233 32/143 (22%)
Periplasmic_Binding_Protein_Type_2 297..>391 CDD:328725 25/98 (26%)
Periplasmic_Binding_Protein_Type_2 <496..637 CDD:328725 26/146 (18%)
grik1bXP_690040.5 Periplasmic_Binding_Protein_Type_1 62..455 CDD:299141 2/12 (17%)
ANF_receptor 80..423 CDD:279440
Periplasmic_Binding_Protein_Type_2 471..840 CDD:304360 77/436 (18%)
Lig_chan 602..871 CDD:278489 55/338 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170591586
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.840

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