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Protein Alignment Ir40a and Gria3

DIOPT Version :9

Sequence 1:	NP_610140.4	Gene:	Ir40a / 35449	FlyBaseID:	FBgn0259683	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_001268858.2	Gene:	Gria3 / 53623	MGIID:	95810	Length:	888	Species:	Mus musculus

Alignment Length:	587	Identity:	117/587 - (19%)
Similarity:	216/587 - (36%)	Gaps:	135/587 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 VTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGDNLGLQRIPLLPTALSVYANFKGRTFRV-PVFH 224
            |:..||..:...|.:..|.||.|:      ..|:                ::.:.||..| .:..
Mouse   384 VSGSRKAGYWNEYERFVPFSDQQI------SNDS----------------SSSENRTIVVTTILE 426

  Fly   225 SPPWFWVTYCNN--SFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQ 287
            ||   :|.|..|  ..|.:|.:.              |....|...::||:..::| :...|..:
Mouse   427 SP---YVMYKKNHEQLEGNERYE--------------GYCVDLAYEIAKHVRIKYK-LSIVGDGK 473

  Fly   288 GSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFS--FFTLADSGAFATHAPR 350
            ...|..:.|..|    |.:|.|..|:||..:..:.::..|.:.|:||  |.:|..|  .....|:
Mouse   474 YGARDPETKIWN----GMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGIS--IMIKKPQ 532

  Fly   351 RLNEAL-AIMRPFKQDIWPHLILTIIFSGPIFYGIIAL--------PYIWRRRWANSDVEHLGEL 406
            :....: :.:.|...:||    :.|:|:   :.|:..:        ||.|.....|.:
Mouse   533 KSKPGVFSFLDPLAYEIW----MCIVFA---YIGVSVVLFLVSRFSPYEWHLEDNNEE------- 583

  Fly   407 YIHMTYLKEITPRLLKLKPRTVLSAHQMPHQ--LFQKCIWFTLRLFLKQSCNELHNGYRAKFLTI 469
                              ||...|....|::  :|.. :||:|..|::|.|:........:.:..
Mouse   584 ------------------PRDPQSPPDPPNEFGIFNS-LWFSLGAFMQQGCDISPRSLSGRIVGG 629

  Fly   470 VYWIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGYRLYVEKESSSLEMLENGT- 533
            |:|. .|.::...|:|.|.:.........||.:.:.|            .::...:...|::|:
Mouse   630 VWWF-FTLIIISSYTANLAAFLTVERMVSPIESAEDL------------AKQTEIAYGTLDSGST 681

  Fly   534 -ELFRQ----LYALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYGSNN 593
             |.||:    :|..|...:.:.....|..:...|:..:.:.....|.|.......:..|:...:.
Mouse   682 KEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDT 746

  Fly   594 FQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQ 658
            .::...|.::...||...|......:|..:::|.|.|||||:.    .|.:.:       ||...
Mouse   747 MKVGGNLDSKGYGVATPKGSALRTPVNLAVLKLSEQGILDKLK----NKWWYD-------KGECG 800

  Fly   659 AKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLA-AGVILLLEIVFIKLDQARLWMLCSR 722
            ||:|.:..:|        |.|:|..:.|.|..| ||.|. |.::.|:|..:....:::...|...
Mouse   801 AKDSGSKDKT--------SALSLSNVAGVFYIL-VGGLGLAMMVALIEFCYKSRAESKRMKLTKN 856

  Fly   723 LQ 724
            .|
Mouse   857 TQ 858

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.