DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ir40a and grid2

DIOPT Version :9

Sequence 1:NP_610140.4 Gene:Ir40a / 35449 FlyBaseID:FBgn0259683 Length:732 Species:Drosophila melanogaster
Sequence 2:NP_001004123.1 Gene:grid2 / 448841 ZFINID:ZDB-GENE-040913-1 Length:1009 Species:Danio rerio


Alignment Length:515 Identity:105/515 - (20%)
Similarity:190/515 - (36%) Gaps:131/515 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   212 NFKGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFR 276
            |.:|...||......|:..|:  .|...:.:::... ||:             :|..|:.::.|:
Zfish   437 NMRGVVLRVVTVLEEPFVMVS--ENVLGKPKKYQGF-SID-------------VLDALANYLGFK 485

  Fly   277 FKYIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFSFFTLADS 341
            ::...||....||.:: ||     ::.|.||.|...:||..|..:.::.||...::|:...:..|
Zfish   486 YEIYVAPDHKYGSQQA-DG-----TWNGLIGELVFKRADVGLSALTITPERESVVDFTTRYMDYS 544

  Fly   342 GAFATHAPRRLNEALAIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIWRRRWANSDVEHLGEL 406
            .........|..:..|.:.||...:|..:..|::..|.:.|.:         .|.|         
Zfish   545 VGVLLRKAERTVDMFACLAPFDLSLWACIAGTVLLVGTLVYLL---------NWLN--------- 591

  Fly   407 YIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCNELHNGYRAKFLTIVY 471
                      .|||    |...:|:..:.:.:     ||....|::|.....:.....:.:..|:
Zfish   592 ----------PPRL----PMGSVSSTTLYNSM-----WFVYGSFVQQGGEVPYTTLATRMMMGVW 637

  Fly   472 WIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGYRLYVEKESSSLEMLENGTELF 536
            |:.|..|::. |:|.|.:.......|..|.:||.|             .|::.    |..||.|.
Zfish   638 WLFALIVISS-YTANLAAFLTISRIENSIQSLQDL-------------AKQTD----LPYGTVLD 684

  Fly   537 RQLYALMRQQVIN----DPQ-----------GFFIDSVE---AGIKLIAEGG----EDKAVLGGR 579
            ..:|..:|.:.:|    ||.           |...::||   .||:.:..|.    .|.|||.  
Zfish   685 SAVYDQVRSKGMNPFERDPMYSQMWRMINRTGGAENNVEESKEGIRKVKYGRFAFVWDAAVLE-- 747

  Fly   580 ETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAAEYAKQY 644
               :..:.....:.:.:|..:..|...:|:|.|.|:....:..:::|.::|.:|           
Zfish   748 ---YVAINDEDCSLYTVSNNVADRGYGMAMQHGSPYRDIFSQRILELQQNGDMD----------- 798

  Fly   645 QEVEATRIYKGSVQAKNS--EAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLAAGVIL 702
                   |.|.....::|  :.||...:..|.  |.|::....|.|..     |||||:|
Zfish   799 -------ILKLKWWPRDSPCDLYSPVGTRKSG--SALDIHSFAGVFFV-----LAAGVVL 844

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ir40aNP_610140.4 PBP2_LTTR_substrate 216..338 CDD:330233 26/121 (21%)
Periplasmic_Binding_Protein_Type_2 297..>391 CDD:328725 19/93 (20%)
Periplasmic_Binding_Protein_Type_2 <496..637 CDD:328725 34/162 (21%)
grid2NP_001004123.1 PBP1_iGluR_delta_2 28..427 CDD:107386
ANF_receptor 42..404 CDD:279440
PBP2_iGluR_delta_2 440..806 CDD:270449 90/465 (19%)
Lig_chan 568..841 CDD:278489 68/357 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 989..1009
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170591513
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.840

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