Protein Alignment Ir40a and gria3b

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_938174.1
• Gene: gria3b / 368416
• ZFINID: ZDB-GENE-030616-53
• Length: 883
• Species: Danio rerio
• Alignment Length: 539
• Identity: 107/539 - (19%)
• Similarity: 201/539 - (37%)
• Gaps: 134/539 - (24%)

  Fly   229 FWVTYCNNSFEE-----DEEF-NSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQ 287
            :|     |.||.     |::| |...|:|.|.:.||...:...:|....||     ::|...:.:
Zfish   388 YW-----NEFERFVNIMDQQFTNDSSSVENRTIVVTTIMEAPYVMYKKNHM-----HLEGNEKYE 442

  Fly   288 G---SMRSE---------------DGK-----DSNDSFTGGIGLLQSGQADFFLGDVGLSWERRK 329
            |   .:.||               |||     ....|:.|.:|.|..|:||..:..:.::..|.:
Zfish   443 GYCVDLASEIAKHVGIKYRLSIVMDGKYGARDPETKSWNGMVGELVYGRADIAVAPLTITLVREE 507

  Fly   330 AIEFS--FFTLADSGAFATHAPRRLNEAL-AIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIW 391
            .|:||  |.:|..|  .....|::....: :.:.|...:||    :.|:|:   :.|:..:.::.
Zfish   508 VIDFSKPFMSLGIS--IMIKKPQKSKPGVFSFLDPLAYEIW----MCIVFA---YIGVSVVLFLV 563

  Fly   392 RR----RWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQ--LFQKCIWFTLRLF 450
            .|    .|...:.:.:.:                   |:|   ....|:.  :|.. :||:|..|
Zfish   564 SRFSPYEWQLDETDEVKD-------------------PQT---PPDPPNDFGIFNS-LWFSLGAF 605

  Fly   451 LKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGY 515
            ::|.|:........:.:..|:|. .|.::...|:|.|.:.........||.:.:.|
Zfish   606 MQQGCDISPRSLSGRIVGGVWWF-FTLIIISSYTANLAAFLTVERMVSPIESAEDL--------- 660

  Fly   516 RLYVEKESSSLEMLENGT--ELFRQ----LYALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDKA 574
               .::...:...|::|:  |.||:    :|..|...:.:.....|..:...|:..:.:.....|
Zfish   661 ---AKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFAKTTPDGVARVRKSKGKFA 722

  Fly   575 VLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAAE 639
            .|.......:..|:...:..::...|.::...||...|.....::|..:::|.|.|:|||:
Zfish   723 FLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRNAVNLAVLKLNEQGLLDKL---- 783

  Fly   640 YAKQYQEVEATRIYKGSVQAKNSEAYSRTE-------SYDSTVISPLNLRMLQGAFIALGVGSLA 697
                                ||...|.:.|       |.|.|  |.|:|..:.|.|..| ||.|.
Zfish   784 --------------------KNKWWYDKGECGSGGGDSKDKT--SALSLSNVAGVFYIL-VGGLG 825

  Fly   698 -AGVILLLEIVFIKLDQAR 715
             |.::.|:|..:....:|:
Zfish   826 LAMMVALIEFCYKSRAEAK 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	21/95 (22%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	21/96 (22%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	26/146 (18%)
gria3b	NP_938174.1	Periplasmic_Binding_Protein_type1	25..398	CDD:471960	4/14 (29%)
		PBP2_iGluR_AMPA	412..794	CDD:270433	81/455 (18%)