Protein Alignment Ir40a and Ir48b

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_610697.1
• Gene: Ir48b / 36254
• FlyBaseID: FBgn0033648
• Length: 600
• Species: Drosophila melanogaster
• Alignment Length: 749
• Identity: 150/749 - (20%)
• Similarity: 246/749 - (32%)
• Gaps: 266/749 - (35%)

  Fly    43 LQQSS-----LAILALPSL---ALSDGVCQKER-----------------NVYLDDFLQRLHRSN 82
            |||||     |.:||:.|:   .|:|.:.:..:                 |.|...:||  |...
  Fly     3 LQQSSNLLKLLLLLAISSVRTQGLNDIIIELNQRLLISNNFLYCNQSDKLNEYEIKYLQ--HMPP 65

  Fly    83 YKSVVFSQTE-LFFQHIEENLQGANECISLILDEPNQLLNSLHDRHLGHRLSLFIFYWGARWPPS 146
            ...::|:..| :.|..:|.|| ||:..:.||:.......:.||..:|..:.:.:|
  Fly    66 ISLMIFTSIESMNFTQVEYNL-GADNKLFLIMGNEEPPYDFLHALNLHFQFAEYI---------- 119

  Fly   147 SRVIRFREPLRVVVVTRP--RKKAFRIYYNQARPCSDSQLQLVN--WYDGDNLGLQRIPLLPTAL 207
                        :|:..|  .||            |...|..||  |..|      .:.||
  Fly   120 ------------IVIDEPVDLKK------------STKWLDFVNHLWQQG------YVQLL---- 150

  Fly   208 SVYANFKGRTFRVPVFHSPPWFWVTYCNNSFEED--EEF----NSLDSIEKRKVRVTGGRDHRLL 266
             :|.::..:     ::|.     :.:.....||.  |::    .|.:::....|||....:....
  Fly   151 -IYTSYDEK-----LYHK-----IIFPETVIEETLVEQYISIRGSFNNLYGYPVRVAAYNNAPRS 204

  Fly   267 MLL----SKH------MNFRFKYIEA--------------PGRTQGSMRSEDGKDSNDSFTGGIG 307
            ||.    .||      |.|...:|:|              ||....::.:|......|:
  Fly   205 MLYVNRWGKHIFAGFYMRFLRAFIDARNGSFVPVLTPSNSPGNCTLNLVNETVDVCADA------ 263

  Fly   308 LLQSGQADFFL--GDVGLSWERRKAIEFSFFTLADSGAFATHAPRRLNEALAIMRPFKQDIWPHL 370
             |.:..|.|.|  |                |.:|.:....||| :.|:....:..||:..:|..|
  Fly   264 -LAANPAAFSLTHG----------------FRIASANVLVTHA-KPLHSYRYLTAPFQWSVWACL 310

  Fly   371 ILTIIFSGPIFYGIIALPYI-WRR--RWANSD--VEHLGELYIHMTYLKEITPRLLKLKPRTVLS 430
            ::.::..      :..|.:| |.|  :|..|.  :|....|.....|||||..|
  Fly   311 VIYVLLV------VNFLSFIGWLRSGKWEFSKYLLEVFSSLLFSGFYLKEIRGR----------- 358

  Fly   431 AHQMPHQLFQKCIWFTLRLFLKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPA 495
                     ::.|.|.: ||:                       |.:|.:..|...|.|......
  Fly   359 ---------ERYILFGV-LFI-----------------------AGFVYSTEYLGLLKSMLISEV 390

  Fly   496 REPPINTLQRLQAAMIHDGYRLYVEKESSSLEMLENGTELFRQLYALMRQQVINDPQGFFIDSVE 560
            .|..|:|.:    |::.....|.|:.....|....|..|:...:..|:              |.|
  Fly   391 FEKQIDTFE----ALVESNITLMVDPYDKILFAKYNMPEILSPIMELV--------------SFE 437

  Fly   561 AGIKLIAEGGEDKA--VLGGRETLFFNVQQYGSN--------NFQLSQKLYTRYSAVAVQIGCP- 614
            ..:|......:|.|  :...|..|:...||:..:        :|..   |||         |.|
  Fly   438 TLLKHRNRFDQDYAYILFSDRMALYDYAQQFLKHPKLLRIPIDFSF---LYT---------GIPM 490

  Fly   615 ----FL-GSLNNVLMQLFESGILDKMTA-AEYAKQYQEVEATRI-YKGSVQAKNSEAYSRTESYD 672
                || ..|.......||||:..|:.. |::       ||.|: |...:..::.||
  Fly   491 RKRWFLKHHLGRAWYWAFESGLTRKLALDADF-------EAVRVGYLSFLITEHVEA-------- 540

  Fly   673 STVISPLNLRMLQGAFIALGVGSLAAGVILLLEI 706
                .|||:.......|||.:|.:.|.:..::|:
  Fly   541 ----QPLNVDYFVMPAIALAIGYILALLSFVIEM 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	17/96 (18%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	18/96 (19%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	33/156 (21%)
Ir48b	NP_610697.1	None