Protein Alignment Ir40a and Ir67c

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_729609.1
• Gene: Ir67c / 317838
• FlyBaseID: FBgn0052058
• Length: 573
• Species: Drosophila melanogaster
• Alignment Length: 701
• Identity: 122/701 - (17%)
• Similarity: 226/701 - (32%)
• Gaps: 233/701 - (33%)

  Fly    64 QKERNVYLDDFLQRLHRSNYKSVVFSQ--TELFFQHIEENLQ--GANECISLIL-----DEPNQL 119
            |.:.|:|||        .|...:...|  :.||.....:.::  |.....|||:     ...|:.
  Fly    34 QLQLNIYLD--------CNDVELQIGQEVSNLFVNSTADKMKILGRFSSHSLIIACFKDSTRNRT 90

  Fly   120 LNSLHDRHLGHRLSLFIFYWGARWPPSSRVIRFREPLRVVVVTRPRKKAFRIYYNQARPCSDSQL 184
            ||.:.:           ..||.::.|...|:               ......|:.||.......:
  Fly    91 LNGVKE-----------LLWGLQYLPILFVV---------------DSNMDFYFQQALRHGFIHV 129

  Fly   185 QLVNWYDGDNLGLQRIPLLPT----------ALSVYANFKGRTFRVPVFHSPPWFWVTYCNNSFE 239
            ..:|:.:|.....:..|.:..          .|:...|.:|:..|..|....|        ..|.
  Fly   130 LALNFMNGSLYTYKPYPKVEVHQIKDMQKFYKLTKLRNLQGQAVRTTVETMTP--------RCFR 186

  Fly   240 EDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQGSMRSEDGKDSNDSFTG 304
            .......|         |..|..:|::.......|             |:.....|......:..
  Fly   187 YRNRHGQL---------VYAGYMYRMVKEFISTYN-------------GTEEHVFGNVDTVPYKE 229

  Fly   305 GIGLLQSGQADFFLGDVGLSWERRKAIEFSFFTLADSGAFATHA------------PRRLNEALA 357
            |:..|::|:.|.....:       .|:|:.:|       :.:|.            ...|.::|.
  Fly   230 GLAALKNGEIDMMPRII-------HALEWYYF-------YRSHILYNIKTYIMVPWAEPLPKSLY 280

  Fly   358 IMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIWRRRWANSDVEHLGELYIHMTYLKEITPRLLK 422
            .::||:..:|    :||:.|  ..|..|.:.:|..|:..||.:
  Fly   281 FIQPFRGTVW----ITIMVS--FVYASIVIWWIRYRQQGNSSL---------------------- 317

  Fly   423 LKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQL 487
              .::.:...|:..||....||            ..:.|.......||.::.. ::|.::|:|||
  Fly   318 --TQSFMDVLQLLFQLPLSKIW------------HFNMGTHQVVSFIVLFVFG-FMLTNLYTAQL 367

  Fly   488 TSQFARPAREPPINT------------LQRLQAAMIHDGYR-LYVEKESSSLEMLENGTELFRQL 539
            :|.......:..|||            ::...|.::|:..: ..::||..|:.::.:..|:|:
  Fly   368 SSYLTTGLFKSQINTFDDLFREKRTLLVESFDAEVLHNMTKEKIIQKEFESIILITSIEEVFK-- 430

  Fly   540 YALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRY 604
                .::.:|....:             |..||:..                  |:|||:.|.|.
  Fly   431 ----HRKSLNTSYAY-------------EAYEDRIA------------------FELSQQRYLRV 460

  Fly   605 SA--------------VAVQIGCPFLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKG 655
            ..              ||::.|.|::...||.|.::|||||..|:....:.:        .|..|
  Fly   461 PIFKILKEVYDQRPVFVALRHGLPYVELFNNYLRRIFESGIWIKLQEDSFLE--------GIASG 517

  Fly   656 SVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLAAGVILLLEI 706
            .:..:.|:         |..|...:......|:|.||:|...:.:.|.||:
  Fly   518 EISFRKSK---------SREIKIFDKDFYFFAYILLGMGWCVSTIALFLEL 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	9/70 (13%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	18/105 (17%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	33/167 (20%)
Ir67c	NP_729609.1	7tm_GPCRs	<279..357	CDD:475119	21/120 (18%)
		TM helix 5	279..306	CDD:320097	9/32 (28%)