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Protein Alignment Ir40a and Gria3

DIOPT Version :9

Sequence 1:	NP_610140.4	Gene:	Ir40a / 35449	FlyBaseID:	FBgn0259683	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_001106213.1	Gene:	Gria3 / 29628	RGDID:	70958	Length:	888	Species:	Rattus norvegicus

Alignment Length:	594	Identity:	116/594 - (19%)
Similarity:	213/594 - (35%)	Gaps:	149/594 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 VTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGDNLGLQRIPLLPTALSVYANFKGRTFRV-PVFH 224
            |:..||..:...|.:..|.||.|:      ..|:                ::.:.||..| .:..
  Rat   384 VSGSRKAGYWNEYERFVPFSDQQI------SNDS----------------SSSENRTIVVTTILE 426

  Fly   225 SPPWFWVTYCNN--SFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQ 287
            ||   :|.|..|  ..|.:|.:.              |....|...::||:..::| :...|..:
  Rat   427 SP---YVMYKKNHEQLEGNERYE--------------GYCVDLAYEIAKHVRIKYK-LSIVGDGK 473

  Fly   288 GSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFS--FFTLADSGAFATHAPR 350
            ...|..:.|..|    |.:|.|..|:||..:..:.::..|.:.|:||  |.:|..|  .....|:
  Rat   474 YGARDPETKIWN----GMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGIS--IMIKKPQ 532

  Fly   351 RLNEAL-AIMRPFKQDIWPHLILTIIFSGPIFYGIIAL--------PYIWRRRWANSDVEHLGEL 406
            :....: :.:.|...:||    :.|:|:   :.|:..:        ||.|.....|.:
  Rat   533 KSKPGVFSFLDPLAYEIW----MCIVFA---YIGVSVVLFLVSRFSPYEWHLEDNNEE------- 583

  Fly   407 YIHMTYLKEITPRLLKLKPRTVLSAHQMPHQ--LFQKCIWFTLRLFLKQSCNELHNGYRAKFLTI 469
                              ||...|....|::  :|.. :||:|..|::|.|:........:.:..
  Rat   584 ------------------PRDPQSPPDPPNEFGIFNS-LWFSLGAFMQQGCDISPRSLSGRIVGG 629

  Fly   470 VYWIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGYRLYVEKESSSLEMLENGT- 533
            |:|. .|.::...|:|.|.:.........||.:.:.|            .::...:...|::|:
  Rat   630 VWWF-FTLIIISSYTANLAAFLTVERMVSPIESAEDL------------AKQTEIAYGTLDSGST 681

  Fly   534 -ELFRQ----LYALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYGSNN 593
             |.||:    :|..|...:.:.....|..:...|:..:.:.....|.|.......:..|:...:.
  Rat   682 KEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDT 746

  Fly   594 FQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQ 658
            .::...|.::...||...|.....::|..:::|.|.|:|||:
  Rat   747 MKVGGNLDSKGYGVATPKGSALGNAVNLAVLKLNEQGLLDKL----------------------- 788

  Fly   659 AKNSEAYSRTE-------SYDSTVISPLNLRMLQGAFIALGVGSLA-AGVILLLEIVFIKLDQAR 715
             ||...|.:.|       |.|.|  |.|:|..:.|.|..| ||.|. |.::.|:|..:....:::
  Rat   789 -KNKWWYDKGECGSGGGDSKDKT--SALSLSNVAGVFYIL-VGGLGLAMMVALIEFCYKSRAESK 849

  Fly   716 LWMLCSRLQ 724
            ...|....|
  Rat   850 RMKLTKNTQ 858

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.