Protein Alignment Ir40a and GRIN2C

DIOPT Version :9

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_016880033.1
• Gene: GRIN2C / 2905
• HGNCID: 4587
• Length: 1337
• Species: Homo sapiens
• Alignment Length: 512
• Identity: 93/512 - (18%)
• Similarity: 172/512 - (33%)
• Gaps: 165/512 - (32%)

  Fly   265 LLMLLSKHMNFRFK-YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERR 328
            :|..|::.:.|.:. |:...|:        .||.....:.|.||.:...:||..:|.:.::.||.
Human   536 ILKKLARVVKFSYDLYLVTNGK--------HGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERS 592

  Fly   329 KAIEFSFFTLADSGAFATHAPRRLNEAL---AIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYI 390
            :.::|| ....::|.....|  |.|..:   |.:.|:...:|..:.:..:       .::|:...
Human   593 EIVDFS-VPFVETGISVMVA--RSNGTVSPSAFLEPYSPAVWVMMFVMCL-------TVVAITVF 647

  Fly   391 WRRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSC 455
                        :.|.:..::|.:.:|.......|...:.          |.:|....|....|.
Human   648 ------------MFEYFSPVSYNQNLTRGKKSGGPAFTIG----------KSVWLLWALVFNNSV 690

  Fly   456 N-ELHNGYRAKFLTIVYWIAATYVLADVYSAQL-------------------------------- 487
            . |...|..:|.:.:|:...|...||. |:|.|
Human   691 PIENPRGTTSKIMVLVWAFFAVIFLAS-YTANLAAFMIQEQYIDTVSGLSDKKSLHLENTGVAWT 754

  Fly   488 ------TSQFARPARE-PPI---------------NTLQRLQAAMIHDGYRLYVEKESSSLEMLE 530
                  :..|.||..: ||.               :..:.:...|:....| .||...:||:|..
Human   755 AFKTFCSDYFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQR-SVEDALTSLKMGS 818

  Fly   531 NGTELFRQLYALMRQ-QVINDPQGFFIDSVEAGIKLIAEG-GEDKAVLGGRETLFFNVQQYGSNN 593
            ....:.|:|.|.:.. .|:|     ::...:.|.||:..| |:..|..|           ||
Human   819 EAQPVPRKLDAFIYDAAVLN-----YMAGKDEGCKLVTIGSGKVFATTG-----------YG--- 864

  Fly   594 FQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQ 658
                         :|:|....:..:::..|:|....|            :.|::|...: .|..|
Human   865 -------------IAMQKDSHWKRAIDLALLQFLGDG------------ETQKLETVWL-SGICQ 903

  Fly   659 AKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLAAGVILLL----EIVFIKL 711
            .:.:|..|          |.|::..:.|.|..|.|   |.|:.||:    .:|:.||
Human   904 NEKNEVMS----------SKLDIDNMAGVFYMLLV---AMGLALLVFAWEHLVYWKL 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	PBP2_LTTR_substrate	216..338	CDD:330233	17/73 (23%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:328725	18/96 (19%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:328725	28/158 (18%)
GRIN2C	XP_016880033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156157
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840