Protein Alignment Ir40a and Ir51b

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_725440.1
• Gene: Ir51b / 246442
• FlyBaseID: FBgn0050081
• Length: 597
• Species: Drosophila melanogaster
• Alignment Length: 785
• Identity: 143/785 - (18%)
• Similarity: 258/785 - (32%)
• Gaps: 279/785 - (35%)

  Fly     1 MHKFLALGLLPYLLGLLN---------------STRLTFI-----------GNDESDTAIALTQI 39
            |.|.|.|.::..||.|.|               |||..:|           |.|.:|..|.|.|.
  Fly     1 MCKVLTLLVVILLLALTNAAYNVTLLKSVLSLISTREPWINTPIFVGHNTQGGDLNDLIIWLHQT 65

  Fly    40 VRGLQQSSLAILALPSLALSDGVCQKERNVYLDDFLQRLH---RSNYKSVVFSQTELFFQH---- 97
            :                    ||.....|:    |||..|   ..::|...::...|||.|
  Fly    66 M--------------------GVTSLTMNL----FLQPEHIRPLGHFKITRYNGIALFFCHDKHD 106

  Fly    98 -----IEENLQGANECISLILDEPNQLLNSLHDRHLGHRLSLFIFYWGARWPPSSRVIRFREPLR 157
                 ::.||:.... |.||:...||...|     .|...|:|...|..::            |.
  Fly   107 IMWLTLDRNLRKLRR-IRLIIILRNQRSGS-----QGAIKSIFNALWQYQF------------LN 153

  Fly   158 VVVVTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGDNLGLQRIPLLPTALSVYANFKGRTFRVPV 222
            |:|:.|.:..::..|            ..:.::   .|.:...||.|.|.   .||.|.....|.
  Fly   154 VLVLQRDQLYSYTPY------------PAMRFF---KLDIHTEPLFPHAA---RNFHGYVVSTPA 200

  Fly   223 FHSPPWFWVTYCNNSFEEDEEFNSLDSIEK-RKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRT 286
            .:..|              ..|:..|.:.| |||.   |..:|..:....|.|
  Fly   201 ENDIP--------------RVFHVHDPLTKSRKVL---GYAYRTFVEYLDHYN------------ 236

  Fly   287 QGSMRSEDGKDSNDSFTGG-----IGLLQSGQADFFLGDVGLSWERRKAIEFSFFTLADSGAFAT 346
             .|:|..:..::.|..|..     :.|:..||                 :|.|......:...||
  Fly   237 -ASLRLTNPDENLDPTTSVNMNHIVQLIIDGQ-----------------LEISLHPYVFTPPTAT 283

  Fly   347 HA------------PRRLNEA---LAIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIWRRRWA 396
            .:            |.| ||.   :.::|||:...|..|:..:.:...|.|.|  .|.:.:..|.
  Fly   284 KSYPLLIYPNCLIVPMR-NEIPRHMYLLRPFQLYSWYILLFAVFYITGILYCI--SPKLNKSSWP 345

  Fly   397 NSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCNELHNG 461
                :.||     :.:|..|:..|....|.|:           .:..|..|.:||:
  Fly   346 ----QRLG-----LNFLDAISKILFISPPITI-----------YRPTWRHLIIFLQ--------- 381

  Fly   462 YRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGYRLYVEKESSSL 526
                 |:::.:::.::     |:.:|.|.|........:|::.:|    :|...|:.|::
  Fly   382 -----LSVLGFMSTSW-----YNIELDSFFTTIVVGEQVNSMDQL----VHQQQRVLVKE----- 427

  Fly   527 EMLENGTELFRQLYALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDKAVLGGRETL--------- 582
                      .::...:|..   :|:  .::.|...:..:....:..|:|....:.
  Fly   428 ----------YEINTFLRHV---EPR--LVEKVSRLLVPVNASEQVSALLSFNRSFAYPFTEERW 477

  Fly   583 -FFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLG-----------SLNNVLMQLFESGILDKM 635
             ||.:||      |.:.|...|:|:..  :|.|.:|           |||:.::::.::|:|:..
  Fly   478 QFFAMQQ------QYAFKPIFRFSSAC--LGSPHIGYPMRVDSHLETSLNHFILKIQDTGLLNHW 534

  Fly   636 TAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLAAGV 700
            ..::             :..:::|...........|.|..:..|.|     .:..||:|.:.:.:
  Fly   535 VVSD-------------FNDAMRAGYVRFVDNVLGYQSIDVDTLRL-----GWCVLGIGWILSAL 581

  Fly   701 ILLLE 705
            :...|
  Fly   582 VFSCE 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	11/75 (15%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	22/113 (19%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	26/161 (16%)
Ir51b	NP_725440.1	None