Protein Alignment Ir40a and Grin2d

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_063136781.1
• Gene: Grin2d / 24412
• RGDID: 2740
• Length: 1356
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 93/521 - (17%)
• Similarity: 160/521 - (30%)
• Gaps: 186/521 - (35%)

  Fly    33 AIALTQIVRGLQQSSLAILA----LPSLALSDGVCQKERNVYLDDFLQRLHRSNYKSVVFSQTEL 93
            |..:..:.||.|    |:|.    ||.|...   |:.:...:..:.|.|.    :.::.:...:.
  Rat   318 AAGVAVVARGAQ----ALLRDYGFLPELGHD---CRTQNRTHRGESLHRY----FMNITWDNRDY 371

  Fly    94 FFQHIEENLQGANECISLILDEPNQLLNSLHDRHLGHRLSLFIFYWGARWPPSSRVIRFREPL-- 156
            .|......:..:...|||..|...:::.|...:.|  ||         ::|..||..||.:|:
  Rat   372 SFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTL--RL---------KYPLWSRYGRFLQPVDD 425

  Fly   157 -----------RVVVVTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGDNLGLQRIPLLPTALSVY 210
                       |..|:..|...........:.||. |||
  Rat   426 TQHLTVATLEERPFVIVEPADPISGTCIRDSVPCR-SQL-------------------------- 463

  Fly   211 ANFKGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNF 275
                .||      ||||                    ....:.:.|...|....:|..|:..:.|
  Rat   464 ----NRT------HSPP--------------------PDAPRPEKRCCKGFCIDILKRLAHTIGF 498

  Fly   276 RFK-YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFSFFTLA 339
            .:. |:...|:        .||..:..:.|.||.:...:||..:|.:.::.||.:.::|| ....
  Rat   499 SYDLYLVTNGK--------HGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFS-VPFV 554

  Fly   340 DSGAFATHAPRRLNEAL---AIMRPFKQDIWPHLI---LTII--------FSGPIFYGIIALPYI 390
            ::|.....|  |.|..:   |.:.|:...:|..:.   ||::        :..|:.|.
  Rat   555 ETGISVMVA--RSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYN------- 610

  Fly   391 WRRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQ--KCIWFTLRLFLKQ 453
                                               |::.:..:.....|.  |.||....|....
  Rat   611 -----------------------------------RSLATGKRPGGSTFTIGKSIWLLWALVFNN 640

  Fly   454 SCN-ELHNGYRAKFLTIVYWIAATYVLADVYSAQLTS-----------------QFARPARE-PP 499
            |.. |...|..:|.:.:|:...|...||. |:|.|.:                 :|.||..: ||
  Rat   641 SVPVENPRGTTSKIMVLVWAFFAVIFLAS-YTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPP 704

  Fly   500 I 500
            :
  Rat   705 L 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	17/71 (24%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	21/107 (20%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	2/6 (33%)
Grin2d	XP_063136781.1	None