Protein Alignment Ir40a and gria2b

DIOPT Version :9

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_005157361.1
• Gene: gria2b / 170451
• ZFINID: ZDB-GENE-020125-4
• Length: 897
• Species: Danio rerio
• Alignment Length: 746
• Identity: 135/746 - (18%)
• Similarity: 261/746 - (34%)
• Gaps: 219/746 - (29%)

  Fly    64 QKERNVYLD-------DFLQRL-----HRSNYKSVVFSQTELFFQHIEENLQ-----GANECISL 111
            :|||.|.||       |.::::     |...|..::   ..|.|  ::.:|.     |||.....
Zfish   201 KKERRVILDCEQDKVKDIMEQVITIGRHVKGYHYII---ANLGF--VDGDLSKIQYGGANVSGFQ 260

  Fly   112 ILDEPNQLLNSLHDRHLGHRLSLFIFYWGA----RWPPSSRVIRFREPL---RVVVVTRPRKKAF 169
            |:|..:.|::....|            |.|    .:|.:...||:...|   .|.|:|    :||
Zfish   261 IVDFDDPLVSKFDQR------------WEALEEKEYPGADSKIRYTSALTYDAVQVMT----EAF 309

  Fly   170 RIYYNQ--------------ARPC----------------------------------------- 179
            |..:.|              |.|.
Zfish   310 RYLHKQRIDISRRANNGDCLANPAVPWAQGVEIERALKQVRVDGLTGNIQFDQYGKRVNYTVNVM 374

  Fly   180 ---SDSQLQLVNWYDGDNLGLQRIPLLPTALSVYANFKGRTFRVPVFHSPPWFWVTYCNNSFEED 241
               |:..:::..|.:.|.:.:.:..|.|...   ...:.:|..|......|:..:....:.|.::
Zfish   375 ELKSNGAVKIGYWNEVDKMVVTKSDLFPNDT---MGLENKTVIVTTILEAPYVMLKKNADLFMDN 436

  Fly   242 EEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQGSMRSEDGKDSNDSFTGGI 306
            |.:.              |....|...::||..|::: ::..|..:...|..:.|..|    |.:
Zfish   437 ERYE--------------GYCVDLAAEIAKHCGFKYQ-LKIVGDGKYGARDAETKIWN----GMV 482

  Fly   307 GLLQSGQADFFLGDVGLSWERRKAIEFS--FFTLADSGAFATHAPRRLNEAL-AIMRPFKQDIWP 368
            |.|..|:||..:..:.::..|.:.|:||  |.:|..|  .....|::....: :.:.|...:||
Zfish   483 GELVYGKADIAVAPLTITLVREEVIDFSKPFMSLGIS--IMIKKPQKSKPGVFSFLDPLAYEIW- 544

  Fly   369 HLILTIIFSGPIFYGIIALPYIWRR----RWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVL 429
               :.|:|:   :.|:..:.::..|    .|...:.|. |::                   :|..
Zfish   545 ---MCIVFA---YIGVSVVLFLVSRFSPYEWHTEEYED-GQI-------------------QTNE 583

  Fly   430 SAHQMPHQLFQKCIWFTLRLFLKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARP 494
            |.::.  .:|.. :||:|..|::|.|:........:.:..|:|. .|.::...|:|.|.:.....
Zfish   584 STNEF--GIFNS-LWFSLGAFMRQGCDISPRSLSGRIVGGVWWF-FTLIIISSYTANLAAFLTVE 644

  Fly   495 AREPPINTLQRLQAAMIHDGYRLYVEKESSSLEMLENGT--ELFRQ----LYALMRQQVINDPQG 553
            ....||.:.:.|            .::...:...|::|:  |.||:    |:..|...:......
Zfish   645 RMVSPIESAEDL------------AKQTEIAYGTLDSGSTKEFFRRSKIALFDKMWTYMKGAEPS 697

  Fly   554 FFIDSVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGS 618
            .|:.:...|:..:.:.....|.|.......:..|:...:..::...|.::...:|...|.....:
Zfish   698 VFVKTTAEGVMRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLRNA 762

  Fly   619 LNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTE-------SYDSTVI 676
            :|..:::|.|.|:|||:                        ||...|.:.|       |.:.|
Zfish   763 VNLAVLKLNEQGLLDKL------------------------KNKWWYDKGECGSGGGDSKEKT-- 801

  Fly   677 SPLNLRMLQGAFIALGVGSLAAGVILLLEIV 707
            |.|:|..:.|.|..| ||.|  |:.:|:.:|
Zfish   802 SALSLSNVAGVFYIL-VGGL--GLAMLVALV 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	PBP2_LTTR_substrate	216..338	CDD:330233	25/123 (20%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:328725	21/96 (22%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:328725	25/146 (17%)
gria2b	XP_005157361.1	PBP1_iGluR_AMPA_GluR2	27..395	CDD:107384	37/214 (17%)
		ANF_receptor	55..377	CDD:279440	34/196 (17%)
		PBP2_iGluR_AMPA	410..790	CDD:270433	81/467 (17%)
		Lig_chan	542..820	CDD:278489	63/347 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591642
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840