Protein Alignment Ir40a and Grin2d

DIOPT Version :9

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 535
• Identity: 94/535 - (17%)
• Similarity: 160/535 - (29%)
• Gaps: 197/535 - (36%)

  Fly    33 AIALTQIVRGLQQSSLAILA----LPSLALSDGVCQKERNVYLDDFLQRLHRSNYKSVVFSQTEL 93
            |..:..:.||.|    |:|.    ||.|...   |:.:...:..:.|.|.    :.::.:...:.
Mouse   323 AAGVAVVARGAQ----ALLRDYGFLPELGHD---CRAQNRTHRGESLHRY----FMNITWDNRDY 376

  Fly    94 FFQHIEENLQGANECISLILDEPNQLLNSLHDRHLGHRLSLFIFYWGARWPPSSRVIRFREPL-- 156
            .|......:..:...|||..|...:::.|...:.|  ||         ::|..||..||.:|:
Mouse   377 SFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTL--RL---------KYPLWSRYGRFLQPVDD 430

  Fly   157 -----------RVVVVTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGDNLGLQRIPLLPTALSVY 210
                       |..|:..|...........:.||. |||
Mouse   431 TQHLTVATLEERPFVIVEPADPISGTCIRDSVPCR-SQL-------------------------- 468

  Fly   211 ANFKGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNF 275
                .||..:....|||                    ....:.:.|...|....:|..|:..:.|
Mouse   469 ----NRTHSLVAPRSPP--------------------PDAPRPEKRCCKGFCIDILKRLAHTIGF 509

  Fly   276 RFK-YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFSF---- 335
            .:. |:...|:        .||..:..:.|.||.:...:||..:|.:.::.||.:.::||.
Mouse   510 SYDLYLVTNGK--------HGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVE 566

  Fly   336 -----------FTLADSG--AFATHAPRRLNEALAIMRPFKQDIWPHLI---LTII--------F 376
                       .|::.|.  |||...|....|      |:...:|..:.   ||::        :
Mouse   567 TGISVMVARSNGTVSPSAFLAFAWLMPPMSPE------PYSPAVWVMMFVMCLTVVAVTVFIFEY 625

  Fly   377 SGPIFYGIIALPYIWRRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQ- 440
            ..|:.|.                                          |::.:..:.....|.
Mouse   626 LSPVGYN------------------------------------------RSLATGKRPGGSTFTI 648

  Fly   441 -KCIWFTLRLFLKQSCN-ELHNGYRAKFLTIVYWIAATYVLADVYSAQLTS-------------- 489
             |.||....|....|.. |...|..:|.:.:|:...|...||. |:|.|.:
Mouse   649 GKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLAS-YTANLAAFMIQEEYVDTVSGL 712

  Fly   490 ---QFARPARE-PPI 500
               :|.||..: ||:
Mouse   713 SDRKFQRPQEQYPPL 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	PBP2_LTTR_substrate	216..338	CDD:330233	24/137 (18%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:328725	23/121 (19%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:328725	2/6 (33%)
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:415822	21/113 (19%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	67/404 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846574
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930