Protein Alignment Ir40a and Grin2d

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 535
• Identity: 94/535 - (17%)
• Similarity: 160/535 - (29%)
• Gaps: 197/535 - (36%)

  Fly    33 AIALTQIVRGLQQSSLAILA----LPSLALSDGVCQKERNVYLDDFLQRLHRSNYKSVVFSQTEL 93
            |..:..:.||.|    |:|.    ||.|...   |:.:...:..:.|.|.    :.::.:...:.
Mouse   323 AAGVAVVARGAQ----ALLRDYGFLPELGHD---CRAQNRTHRGESLHRY----FMNITWDNRDY 376

  Fly    94 FFQHIEENLQGANECISLILDEPNQLLNSLHDRHLGHRLSLFIFYWGARWPPSSRVIRFREPL-- 156
            .|......:..:...|||..|...:::.|...:.|  ||         ::|..||..||.:|:
Mouse   377 SFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTL--RL---------KYPLWSRYGRFLQPVDD 430

  Fly   157 -----------RVVVVTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGDNLGLQRIPLLPTALSVY 210
                       |..|:..|...........:.||. |||
Mouse   431 TQHLTVATLEERPFVIVEPADPISGTCIRDSVPCR-SQL-------------------------- 468

  Fly   211 ANFKGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNF 275
                .||..:....|||                    ....:.:.|...|....:|..|:..:.|
Mouse   469 ----NRTHSLVAPRSPP--------------------PDAPRPEKRCCKGFCIDILKRLAHTIGF 509

  Fly   276 RFK-YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFSF---- 335
            .:. |:...|:        .||..:..:.|.||.:...:||..:|.:.::.||.:.::||.
Mouse   510 SYDLYLVTNGK--------HGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVE 566

  Fly   336 -----------FTLADSG--AFATHAPRRLNEALAIMRPFKQDIWPHLI---LTII--------F 376
                       .|::.|.  |||...|....|      |:...:|..:.   ||::        :
Mouse   567 TGISVMVARSNGTVSPSAFLAFAWLMPPMSPE------PYSPAVWVMMFVMCLTVVAVTVFIFEY 625

  Fly   377 SGPIFYGIIALPYIWRRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQ- 440
            ..|:.|.                                          |::.:..:.....|.
Mouse   626 LSPVGYN------------------------------------------RSLATGKRPGGSTFTI 648

  Fly   441 -KCIWFTLRLFLKQSCN-ELHNGYRAKFLTIVYWIAATYVLADVYSAQLTS-------------- 489
             |.||....|....|.. |...|..:|.:.:|:...|...||. |:|.|.:
Mouse   649 GKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLAS-YTANLAAFMIQEEYVDTVSGL 712

  Fly   490 ---QFARPARE-PPI 500
               :|.||..: ||:
Mouse   713 SDRKFQRPQEQYPPL 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	17/86 (20%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	23/121 (19%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	2/6 (33%)
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:471960	21/113 (19%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	67/404 (17%)