Protein Alignment Ir40a and Grin2c

DIOPT Version :9

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 491
• Identity: 94/491 - (19%)
• Similarity: 172/491 - (35%)
• Gaps: 146/491 - (29%)

  Fly   265 LLMLLSKHMNFRFK-YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERR 328
            :|..|:|.:.|.:. |:...|:        .||.....:.|.||.:...:||..:|.:.::.||.
Mouse   523 ILKKLAKVVKFSYDLYLVTNGK--------HGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERS 579

  Fly   329 KAIEFSFFTLADSGAFATHAPRRLNEAL---AIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYI 390
            :.|:|| ....::|.....|  |.|..:   |.:.|:...:|..:.:..:       .::|:...
Mouse   580 EIIDFS-VPFVETGISVMVA--RSNGTVSPSAFLEPYSPAVWVMMFVMCL-------TVVAITVF 634

  Fly   391 WRRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSC 455
                        :.|.:..::|.:.:|.......|...:.          |.:|....|....|.
Mouse   635 ------------MFEYFSPVSYNQNLTKGKKSGGPSFTIG----------KSVWLLWALVFNNSV 677

  Fly   456 N-ELHNGYRAKFLTIVYWIAATYVLADVYSAQLTS-----------------QFARPARE-PPI- 500
            . |...|..:|.:.:|:...|...||. |:|.|.:                 :|.||..: ||.
Mouse   678 PIENPRGTTSKIMVLVWAFFAVIFLAS-YTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFR 741

  Fly   501 --------------NTLQRLQAAMIHDGYRLYVEKESSSLEMLENGTELFRQLYALMRQ-QVIND 550
                          :..:.:...|:....| .||...:||:|  ....:.|:|.|.:.. .|:|
Mouse   742 FGTVPNGSTERNIRSNYRDMHTHMVKFNQR-SVEDALTSLKM--GARHVSRKLDAFIYDAAVLN- 802

  Fly   551 PQGFFIDSVEAGIKLIAEG-GEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCP 614
                ::...:.|.||:..| |:..|..|           ||                :|:|....
Mouse   803 ----YMAGKDEGCKLVTIGSGKVFATTG-----------YG----------------IAMQKDSH 836

  Fly   615 FLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPL 679
            :..:::..|:|....|            :.|::|...: .|....:.:|..|          |.|
Mouse   837 WKRAIDLALLQFLGDG------------ETQKLETVWL-SGICHNEKNEVMS----------SKL 878

  Fly   680 NLRMLQGAFIALGVGSLAAGVILLL----EIVFIKL 711
            ::..:.|.|..|.|   |.|:.||:    .:|:.||
Mouse   879 DIDNMAGVFYMLLV---AMGLALLVFAWEHLVYWKL 911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	PBP2_LTTR_substrate	216..338	CDD:330233	19/73 (26%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:328725	19/96 (20%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:328725	28/158 (18%)
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	79/433 (18%)
		NMDAR2_C	905..>980	CDD:371139	3/7 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846582
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930