Protein Alignment Ir40a and Grik1

DIOPT Version :9

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_006522977.1
• Gene: Grik1 / 14805
• MGIID: 95814
• Length: 949
• Species: Mus musculus
• Alignment Length: 507
• Identity: 97/507 - (19%)
• Similarity: 181/507 - (35%)
• Gaps: 121/507 - (23%)

  Fly   241 DEEFNSLDSIEKRKVRVTG-----------------GRDH------RLLMLLSKHMNFRFKYIEA 282
            |...|..||:..|.:.||.                 |.|.      .||..||..:.|.:.....
Mouse   435 DRSNNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEGYCLDLLKELSNILGFLYDVKLV 499

  Fly   283 PGRTQGSMRSEDGK--DSND--SFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFS--FFTLADS 341
            |          |||  ..||  .:.|.:..|...:||..:..:.:::.|.|.|:||  |.||..|
Mouse   500 P----------DGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTLGIS 554

  Fly   342 GAFATHAPRRLNEAL-AIMRPFKQDIWPHLILTIIFSGPIFYGIIA--LPYIW-RRRWANSDVEH 402
            ..:  ..|...|..: :.:.|...|||.:::|..:....:.: :||  .||.| .....|.|.:.
Mouse   555 ILY--RKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLF-VIARFTPYEWYNPHPCNPDSDV 616

  Fly   403 LGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCNELHNGYRAKFL 467
            :...:                   |:|::           .||.:...::|....:......:.:
Mouse   617 VENNF-------------------TLLNS-----------FWFGVGALMQQGSELMPKALSTRIV 651

  Fly   468 TIVYWIAATYVLADVYSAQLTSQFARPAREPPINTLQ------RLQAAMIHDGYRLYVEKESSSL 526
            ..::|. .|.::...|:|.|.:.......|.||::..      :::...:.||..:...|:|.
Mouse   652 GGIWWF-FTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSK-- 713

  Fly   527 EMLENGTELFRQLYALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYGS 591
                  ...:.:::|.|..:    .|...:.:.:.||:.:..  .|.|:|....::.: |.|...
Mouse   714 ------ISTYEKMWAFMSSR----QQSALVKNSDEGIQRVLT--TDYALLMESTSIEY-VTQRNC 765

  Fly   592 NNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGS 656
            |..|:...:.::...|...||.|:...:...::||.|.|.|..|             ..:.::|
Mouse   766 NLTQIGGLIDSKGYGVGTPIGSPYRDKITIAILQLQEEGKLHMM-------------KEKWWRG- 816

  Fly   657 VQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLAAGVILLLEIVF 708
                     :.....||...|.|.:..:.|.||.|..|.:.:..:.:.|.::
Mouse   817 ---------NGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFIY 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	PBP2_LTTR_substrate	216..338	CDD:330233	30/125 (24%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:328725	26/100 (26%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:328725	29/146 (20%)
Grik1	XP_006522977.1	PBP1_iGluR_Kainate	38..431	CDD:380605
		Periplasmic_Binding_Protein_Type_2	446..815	CDD:389745	82/440 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846558
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840