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Protein Alignment Ir40a and Gria1

DIOPT Version :9

Sequence 1:	NP_610140.4	Gene:	Ir40a / 35449	FlyBaseID:	FBgn0259683	Length:	732	Species:	Drosophila melanogaster
Sequence 2:	NP_001106796.1	Gene:	Gria1 / 14799	MGIID:	95808	Length:	907	Species:	Mus musculus

Alignment Length:	533	Identity:	101/533 - (18%)
Similarity:	205/533 - (38%)	Gaps:	97/533 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 WYDGDNLGLQRIPLLPTALSVYA-----NFKGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLD 248
            |.:.|.       .:|.|....|     :.:.||:.|......|:..:....|.||.::.:.
Mouse   382 WNEDDK-------FVPAATDAQAGGDNSSVQNRTYIVTTILEDPYVMLKKNANQFEGNDRYE--- 436

  Fly   249 SIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQ 313
                       |....|...::||:.:.:: :|.....:...|..|.|    ::.|.:|.|..|:
Mouse   437 -----------GYCVELAAEIAKHVGYSYR-LEIVSDGKYGARDPDTK----AWNGMVGELVYGR 485

  Fly   314 ADFFLGDVGLSWERRKAIEFS--FFTLADSGAFATHAPRRLNEAL-AIMRPFKQDIWPHLILTII 375
            ||..:..:.::..|.:.|:||  |.:|..|  .....|::....: :.:.|...:||    :.|:
Mouse   486 ADVAVAPLTITLVREEVIDFSKPFMSLGIS--IMIKKPQKSKPGVFSFLDPLAYEIW----MCIV 544

  Fly   376 FSGPIFYGIIALPYIWRR----RWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPH 436
            |:   :.|:..:.::..|    .|.:.:.|                      :.|...::.|...
Mouse   545 FA---YIGVSVVLFLVSRFSPYEWHSEEFE----------------------EGRDQTTSDQSNE 584

  Fly   437 QLFQKCIWFTLRLFLKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPIN 501
            ......:||:|..|::|.|:........:.:..|:|. .|.::...|:|.|.:.........||.
Mouse   585 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWF-FTLIIISSYTANLAAFLTVERMVSPIE 648

  Fly   502 TLQRLQAAMIHDGYRLYVEKESSSLEMLENGTELFRQLYALMRQQVINDPQGFFIDSVEAGIKLI 566
            :.:.| |......|.. :|..|:......:...:|.:::..|:..   :|..|...:.|..|::.
Mouse   649 SAEDL-AKQTEIAYGT-LEAGSTKEFFRRSKIAVFEKMWTYMKSA---EPSVFVRTTEEGMIRVR 708

  Fly   567 AEGGEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGI 631
            ...|:...:|......:.. |:...:..::...|.::...:|...|....|.:|..:::|.|.|:
Mouse   709 KSKGKYAYLLESTMNEYIE-QRKPCDTMKVGGNLDSKGYGIATPKGSALRGPVNLAVLKLSEQGV 772

  Fly   632 LDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSL 696
            |||:.    :|.:.:       ||...:|:|.:..:|        |.|:|..:.|.|..| :|.|
Mouse   773 LDKLK----SKWWYD-------KGECGSKDSGSKDKT--------SALSLSNVAGVFYIL-IGGL 817

  Fly   697 A-AGVILLLEIVF 708
            . |.::.|:|..:
Mouse   818 GLAMLVALIEFCY 830

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.