Protein Alignment CG3635 and LIPF

DIOPT Version :9

• Sequence 1: NP_610138.4
• Gene: CG3635 / 35447
• FlyBaseID: FBgn0032981
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001185758.1
• Gene: LIPF / 8513
• HGNCID: 6622
• Length: 408
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 148/413 - (35%)
• Similarity: 230/413 - (55%)
• Gaps: 25/413 - (6%)

  Fly    18 MANNSPTRGSVMLLTLVLLLLSRKIGLVDG-----H----KVT---ATSISNHNYPVEEHTVITH 70
            |.:|:.:|..:.||..:..|:| .:|...|     |    :||   :..|:...||.||:.|:|.
Human     1 MFSNANSRSKMWLLLTMASLIS-VLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEYEVVTE 64

  Fly    71 DDYILTIYRIPSSPNRSHLNRAGRRAVVFLQHGILSASDDWIINGPEASLAYMLADAGYDVWLGN 135
            |.|||.:.|||.....|  ...|:|.|||||||:|:::.:||.|.|..|||::||||||||||||
Human    65 DGYILEVNRIPYGKKNS--GNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGN 127

  Fly   136 ARGNTYSRQHKHIHPDTSDFWRFSWHEIGVYDLAAMLDYALAKSQSSSLHFVAHSQGTTAFFVLM 200
            :||||::|::.:..||:.:||.||:.|:..|||.|.:|:.:.|:....||:|.||||||..|:..
Human   128 SRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAF 192

  Fly   201 SSLPLYNEKLRSVHLLAPIAYMRDHSFILSKLGGIFLGTPSFLSWVLGSMELLPITNLQKLICEH 265
            |:.|...:::::.:.|||:|.::....:::||..:   ..|...::.|.....|.....:.:...
Human   193 STNPSLAKRIKTFYALAPVATVKYTKSLINKLRFV---PQSLFKFIFGDKIFYPHNFFDQFLATE 254

  Fly   266 ICSSSSMFNFLCSGLLDFIGGWGTRHLNQTLLPDVCATH-PAGASSSQVIHYLQLYRSGDFRQYD 329
            :| |..|.|.|||..|..|.|:.:::.|.:.| ||..:| |||.|...:.|:.|..:||.|:.||
Human   255 VC-SREMLNLLCSNALFIICGFDSKNFNTSRL-DVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYD 317

  Fly   330 HG-PELNEIIYQQPTPPSYNVQYIKSCVDMYYSENDYMSAVGDVKYLASLLPCAQLYR-IPFRDW 392
            .| |..|.:.|.|..||.|||..:...:.::....|.::...||..|...||....:: |||  :
Human   318 WGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKLPNLIYHKEIPF--Y 380

  Fly   393 NHYDFLWSNNVKEVINNKIIQKI 415
            ||.||:|:.:..:.:.|.|:..|
Human   381 NHLDFIWAMDAPQEVYNDIVSMI 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3635	NP_610138.4	Abhydro_lipase	55..115	CDD:282003	27/59 (46%)
		Abhydrolase_1	97..399	CDD:278959	115/304 (38%)
LIPF	NP_001185758.1	PLN02872	14..400	CDD:215470	142/395 (36%)
		Abhydro_lipase	45..107	CDD:282003	27/63 (43%)
		Abhydrolase_5	88..>211	CDD:289465	59/122 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141735
Domainoid	1	1.000	222	1.000	Domainoid score	I2592
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	271	1.000	Inparanoid score	I3005
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.910