DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3635 and MPL1

DIOPT Version :9

Sequence 1:	NP_610138.4	Gene:	CG3635 / 35447	FlyBaseID:	FBgn0032981	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_568295.2	Gene:	MPL1 / 831268	AraportID:	AT5G14180	Length:	418	Species:	Arabidopsis thaliana

Alignment Length:	419	Identity:	127/419 - (30%)
Similarity:	203/419 - (48%)	Gaps:	44/419 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 GSVM---------LLTLVLLLLSRK-------IGLVDGHK--------VTATSISNHNYPVEEHT 66
            ||||         |..|:...||.|       .|.:.|..        :.|:|:....|..|||.
plant     3 GSVMVPSVSIGLALSVLIFFALSLKTLEARGTFGRLAGQPPQRTAAGGICASSVHIFGYKCEEHD 67

  Fly    67 VITHDDYILTIYRIPSSPNRSHLNRAGRRAVVFLQHGILSASDDWIINGPEASLAYMLADAGYDV 131
            |:|.|.|||.:.|||.....:.....|:|..|.:|||||.....|::|..:.:|..:|||.|:||
plant    68 VVTQDGYILNMQRIPEGRAGAVAGDGGKRQPVLIQHGILVDGMSWLLNPADQNLPLILADQGFDV 132

  Fly   132 WLGNARGNTYSRQHKHIHPDTSDFWRFSWHEIGVYDLAAMLDYALAKSQSSSLHFVAHSQGTTAF 196
            |:||.||..:||:||:::|....||.::|.|:..|||.||.|: :.......:|::.||.||...
plant   133 WMGNTRGTRFSRRHKYLNPSQRAFWNWTWDELVSYDLPAMFDH-IHGLTGQKIHYLGHSLGTLIG 196

  Fly   197 FVLMSSLPLYNEKLRSVHLLAPIAYMRDHSFILSKLGGIFLGTPSFL---SWVLGSMELLPITNL 258
            |...|...|. :::||..:|:|:||:   |.:.:.:|.|  ...:||   :.:||..|..|.:.|
plant   197 FASFSEKGLV-DQVRSAAMLSPVAYL---SHMTTVIGDI--AAKTFLAEATSILGWPEFNPKSGL 255

  Fly   259 QKLICEHICSSSSMFNFLCSGLLDFIGGWGTRHLNQTLLPDVCATHPAGASSSQVIHYLQLYRSG 323
            .....:.||..:.:.   |..|:..|.|... .||.:.:....|..|...|:..:||..|..|..
plant   256 VGDFIKAICLKAGID---CYDLVSVITGKNC-CLNASTIDLFLANEPQSTSTKNMIHLAQTVRDK 316

  Fly   324 DFRQYDHG-PELNEIIYQQPTPPSYNVQYIKSCVDMYYSEN--DYMSAVGDVKYLASLLPCAQL- 384
            :.|:|::| .:.|...|.|..||:||:..|...:.:::|..  |.::.|.||::|........:
plant   317 ELRKYNYGSSDRNIKHYGQAIPPAYNISAIPHELPLFFSYGGLDSLADVKDVEFLLDQFKYHDID 381

  Fly   385 -YRIPF-RDWNHYDFLWSNNVKEVINNKI 411
             ..:.| :|:.|.||:.....|:|:.|::
plant   382 KMNVQFVKDYAHADFIMGVTAKDVVYNQV 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3635	NP_610138.4	Abhydro_lipase	55..115	CDD:282003	22/59 (37%)
CG3635	NP_610138.4	Abhydrolase_1	97..399	CDD:278959	96/310 (31%)
MPL1	NP_568295.2	PLN02872	16..415	CDD:215470	123/406 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D651396at2759
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.070