DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3635 and CG31871

DIOPT Version :9

Sequence 1:	NP_610138.4	Gene:	CG3635 / 35447	FlyBaseID:	FBgn0032981	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_723607.1	Gene:	CG31871 / 34463	FlyBaseID:	FBgn0051871	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	419	Identity:	155/419 - (36%)
Similarity:	243/419 - (57%)	Gaps:	25/419 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NSCAQTNILTSKEMANNSPTRGSVMLLTLVLLLLSRKIGLVDGHKVTATSISNHNYPVEEHTVIT 69
            :|.:..|:|.|..:::|....|....|        :...|.|...:|...|..:.||.|.|||:|
  Fly    41 SSLSFKNLLNSVLLSSNPNLAGGGRNL--------KSDVLEDASLITPKLIRKYGYPSETHTVVT 97

  Fly    70 HDDYILTIYRIPSSPNRSHLNRAGRRAVVFLQHGILSASDDWIINGPEASLAYMLADAGYDVWLG 134
            .|.|||.::|||         :.|.:.|: |.||||..|..|::.||::.|.|||:|.|||||:|
  Fly    98 KDGYILEMHRIP---------KKGAQPVL-LMHGILDTSATWVLMGPKSGLGYMLSDLGYDVWMG 152

  Fly   135 NARGNTYSRQHKHIHPDTSDFWRFSWHEIGVYDLAAMLDYALAKSQSSSLHFVAHSQGTTAFFVL 199
            |:|||.||:.|..::.|..:||.|::||:|.|||.|.:||.|:|:....:|::.|||||..|:||
  Fly   153 NSRGNRYSKNHTSLNSDYQEFWDFTFHEMGKYDLPANIDYILSKTGYEQVHYIGHSQGTAIFWVL 217

  Fly   200 MSSLPLYNEKLRSVHLLAPIAYMRDHSFILSKLGGIFLGTPSFLSWVLGSMELLPITNLQKLICE 264
            .|..|.|.:|:.|:|.||||||:.|....|.:...:||...:..:.:|...|.:|.|   |.:.:
  Fly   218 CSEQPAYTQKITSMHALAPIAYIHDMKSPLFRTLVLFLDFLTAATRMLRITEFMPNT---KFLVD 279

  Fly   265 H---ICSSSSMFNFLCSGLLDFIGGWGTRHLNQTLLPDVCATHPAGASSSQVIHYLQLYRSGDFR 326
            |   :|..::|...:||.:|..:.|:.:..||:|:||.:.:..|:|||..|:.|:.||.:||.||
  Fly   280 HSQVVCHDNAMTQDVCSNILFLVAGYNSEQLNKTMLPVMLSHTPSGASIKQLEHFGQLMKSGHFR 344

  Fly   327 QYDHGPELNEIIYQQPTPPSYNVQYIKSCVDMYYSENDYMSAVGDVKYLASLLP-CAQLYRIPFR 390
            ::|.|...|::.|.:.|||.|::..:|..|.:|||.||.:.:...|..||..|| ....|.:|..
  Fly   345 KFDRGYLRNQLEYNRMTPPDYDLSRVKVPVALYYSVNDLLVSTTGVDRLARELPNVIDKYLVPME 409

  Fly   391 DWNHYDFLWSNNVKEVINNKIIQKIRKYD 419
            .:||.||||:.:||.::.|::::.:|:.:
  Fly   410 RFNHLDFLWAIDVKPLVYNRLVRNVRRVE 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3635	NP_610138.4	Abhydro_lipase	55..115	CDD:282003	24/59 (41%)
CG3635	NP_610138.4	Abhydrolase_1	97..399	CDD:278959	123/305 (40%)
CG31871	NP_723607.1	Abhydro_lipase	79..133	CDD:282003	25/63 (40%)
		MhpC	93..436	CDD:223669	140/355 (39%)
		Abhydrolase_5	115..281	CDD:289465	73/169 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439466
Domainoid	1	1.000	150	1.000	Domainoid score	I1414
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900