DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3635 and CG18301

DIOPT Version :9

Sequence 1:	NP_610138.4	Gene:	CG3635 / 35447	FlyBaseID:	FBgn0032981	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_609419.1	Gene:	CG18301 / 34451	FlyBaseID:	FBgn0032265	Length:	422	Species:	Drosophila melanogaster

Alignment Length:	390	Identity:	149/390 - (38%)
Similarity:	225/390 - (57%)	Gaps:	28/390 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LVDGHKVTATSISNHNYPVEEHTVITHDDYILTIYRIPSSPNRSHLNRAGRRAVVFLQHGILSAS 108
            |.|.|..|...||.:.||.|.:||.:.|.|:|.::||.         |.|...|: |.||::.:|
  Fly    39 LEDAHLNTIQLISKYGYPAENYTVQSDDGYLLGLFRIA---------RPGALPVL-LVHGLMDSS 93

  Fly   109 DDWIINGPEASLAYMLADAGYDVWLGNARGNTYSRQHKHIHPDTSDFWRFSWHEIGVYDLAAMLD 173
            |.|::.||.:||.|||.:.|||||:.|.|||||:::|.....:.||||.||:||:|::||.|::|
  Fly    94 DTWVMMGPSSSLGYMLYEQGYDVWMANVRGNTYTKRHVRYSAEDSDFWNFSFHEMGIFDLPAIID 158

  Fly   174 YALAKSQSSSLHFVAHSQGTTAFFVLMSSLPLYNEKLRSVHLLAPIAYMRD-HSFILSKLGGIFL 237
            |.|.:|....||::.||||:|.|::|.|..|.|.||:..:..|||:|::.. .|.|::.|.....
  Fly   159 YILMQSGFGQLHYIGHSQGSTIFWILASERPEYMEKIVMMQALAPVAFLSHCRSPIVNLLASQDT 223

  Fly   238 GTPSFLSWVLGSMELLP----ITNLQKLICEHICSSSSMFNFLCSGLLDFIGGWGTRHLNQTLLP 298
            ...|||| ..|..|.||    |...::..|..|.|||     :|..|...:.|:..:.:|||:||
  Fly   224 AVASFLS-AAGYNEFLPSNSVIDQFKRYACRDIISSS-----VCQSLFFILFGFNGQQVNQTMLP 282

  Fly   299 DVCATHPAGASSSQVIHYLQLYRSGDFRQYDHGPELNEIIYQQPTPPSYNVQYIKSCVDMYYSEN 363
            .|....|||||..|:.||.||..||.|:|:|:| .||.:.|...:||.|.::.:|:.|.:||::|
  Fly   283 IVVGHTPAGASIRQMHHYGQLRNSGKFQQFDYG-LLNFLHYGSLSPPPYELEKVKAKVAIYYAKN 346

  Fly   364 DYMSAVGDVKYLASLLP-CAQLYRIPFRDWNHYDFLWSNNVKEVINNK---IIQKIRKYD--EDG 422
            |:::...||..|.:.|| ..:.|.:|..::||:|.:|..:.|.::.|:   ::|.:..|.  .||
  Fly   347 DWIAPPEDVDMLFNRLPNVVEKYLVPNENFNHFDLVWGRDAKRILWNRMLGVMQSVVPYSSYNDG 411

Fly 423 422
Fly 412 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3635	NP_610138.4	Abhydro_lipase	55..115	CDD:282003	21/59 (36%)
CG3635	NP_610138.4	Abhydrolase_1	97..399	CDD:278959	124/307 (40%)
CG18301	NP_609419.1	Abhydro_lipase	46..100	CDD:282003	22/63 (35%)
		PLN02872	48..407	CDD:215470	143/375 (38%)
		Abhydrolase_5	82..225	CDD:289465	63/143 (44%)
		Abhydrolase_5	<327..379	CDD:289465	17/51 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439464
Domainoid	1	1.000	108	1.000	Domainoid score	I1418
eggNOG	1	0.900	-	-		E2759_KOG2624
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	194	1.000	Inparanoid score	I1354
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D39202at50557
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm1092
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11005
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
	10	9.900