DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3635 and SPBC14C8.15

DIOPT Version :9

Sequence 1:	NP_610138.4	Gene:	CG3635 / 35447	FlyBaseID:	FBgn0032981	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_595918.1	Gene:	SPBC14C8.15 / 2539842	PomBaseID:	SPBC14C8.15	Length:	460	Species:	Schizosaccharomyces pombe

Alignment Length:	377	Identity:	93/377 - (24%)
Similarity:	162/377 - (42%)	Gaps:	48/377 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 HNYPVEEHTVITHDDYILTIYRIPSSPNRSHLNRAGRRAVVFLQHGILSASDDWIIN-GPEASLA 121
            |.|.:|||.|.|.|.|:|.::|: ....:..:........|...||::..|:.|:.| ..|.::.
pombe    82 HGYDLEEHFVRTTDGYLLGLHRV-YKKKKGKIEELNYLPPVLFIHGLMMNSESWVCNLKKEDAIP 145

  Fly   122 YMLADAGYDVWLGNARGNTYSRQHKHIHPDTSDFWRFSWHEIGVYDLAAMLDYALAKSQSSSLHF 186
            :.|.:.||||||||.|||.||.::.........||.||...|.::|:.:::.|.|:.:...|:..
pombe   146 FALVEQGYDVWLGNLRGNKYSIKNIKFSSQNPKFWDFSLDSIAIFDIPSIVKYILSVNSFDSISL 210

  Fly   187 VAHSQGTTAFFVLMSSLPLYNEKLRSVHLLAPIAYMRDHS--------FILSKLGGIFLGTPSFL 243
            |..|||....|..:|........:|:...|||....:.:|        ...|:|..:..|..|.|
pombe   211 VGFSQGAILAFAALSIDTELRNSVRAFIALAPAIAPKKYSGRTVKSIIHANSQLLYLMFGRNSML 275

  Fly   244 -SWVLGSMELLPITNLQKLICEHICSSSSMFNFLCSGLLDFIGGWGTRHLNQTLLPDVCATHPAG 307
             |.|.....|.|                .:|..:....|.|...|..:::::| ...|..:|...
pombe   276 GSAVFWQAVLYP----------------PVFAKIVDLFLRFFLSWTGKNISET-QKIVAYSHLYS 323

  Fly   308 ASSSQ-VIHYLQLYRSGDFRQYDHGP--------ELNEIIYQQPTPPSYNVQYIKSCVDMYYSEN 363
            .:|.: .:|:.|:.|....:.||..|        .||.|       ..|.::.|:..:.:.|..|
pombe   324 FTSVKCFVHWAQITRRKVLQMYDDSPGFKPSYYTNLNRI-------ARYPIENIRLPITLVYGSN 381

  Fly   364 DYMSAVGDVKYLASLLPCAQLYRIPFRDWNHYDFLWSNNVKEVINNKIIQKI 415
            |.|..:..:|  ..|.|.:|..:||  ::.|.|.:..:..|:::..::::::
pombe   382 DNMVDIETLK--TQLPPLSQCIQIP--NYEHLDIIMGDTKKDIVIQQVVEQL 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3635	NP_610138.4	Abhydro_lipase	55..115	CDD:282003	17/57 (30%)
CG3635	NP_610138.4	Abhydrolase_1	97..399	CDD:278959	81/320 (25%)
SPBC14C8.15	NP_595918.1	Abhydro_lipase	75..138	CDD:282003	16/56 (29%)
		Abhydrolase_1	119..412	CDD:278959	81/320 (25%)
		Abhydrolase_5	120..>260	CDD:289465	41/139 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	133	1.000	Domainoid score	I1290
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1188
OMA	1	1.010	-	-		QHG55134
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	1	1.000	-	-		mtm9260
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X80
TreeFam	0	0.000	Not matched by this tool.
	9	8.870