DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clamp and YPR015C

DIOPT Version :9

Sequence 1:	NP_001014498.1	Gene:	Clamp / 35445	FlyBaseID:	FBgn0032979	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_015340.1	Gene:	YPR015C / 856125	SGDID:	S000006219	Length:	247	Species:	Saccharomyces cerevisiae

Alignment Length:	168	Identity:	40/168 - (23%)
Similarity:	70/168 - (41%)	Gaps:	45/168 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   370 CGGLFSRYSSLWSHKKL-----HSGEKNYKCSICGLAFAKAVY-LKNHARIHTGEKPYKCQTCGM 428
            |..::|..:|.::.:.:     |..|:|::      |.:...| |.|   :|.|:.|      |.
Yeast   112 CCPIYSTAASSYTAQSVPPSMQHFQEENHR------AVSNEQYSLPN---VHIGQNP------GT 161

  Fly   429 QFSQSPHLKNHERTHSGERPYV-----CGVCDKGFARHATLWNHRRIHTGEKPYKC--EICGSAF 486
            ..||:.  .:.:......|..|     |.:|.|..:|.:||..|..||||:.|:||  |.|..:|
Yeast   162 LLSQTQ--TDLDLIQKQLRAVVKLRKQCPICGKVCSRPSTLRTHYLIHTGDTPFKCTWEHCNKSF 224

  Fly   487 SQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHR 524
            :..:::..|.:.|.               .:.|.|:|:
Yeast   225 NVKSNMLRHLRTHQ---------------KKIAKKKHQ 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	36/140 (26%)
		C2H2 Zn finger	367..387	CDD:275368	3/21 (14%)
		zf-H2C2_2	379..403	CDD:290200	5/28 (18%)
		C2H2 Zn finger	395..415	CDD:275368	4/20 (20%)
		zf-H2C2_2	407..432	CDD:290200	7/25 (28%)
		C2H2 Zn finger	423..443	CDD:275368	3/19 (16%)
		zf-H2C2_2	435..460	CDD:290200	5/29 (17%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		zf-H2C2_2	464..488	CDD:290200	12/25 (48%)
		COG5048	475..>529	CDD:227381	11/52 (21%)
		C2H2 Zn finger	479..499	CDD:275368	5/21 (24%)
		zf-H2C2_2	491..515	CDD:290200	2/23 (9%)
		C2H2 Zn finger	507..527	CDD:275368	3/18 (17%)
YPR015C	NP_015340.1	COG5048	<17..247	CDD:227381	39/166 (23%)
		C2H2 Zn finger	187..207	CDD:275370	7/19 (37%)
		C2H2 Zn finger	215..237	CDD:275370	5/21 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050