Protein Alignment Clamp and Zfp558

DIOPT Version :10

• Sequence 1: NP_001014498.1
• Gene: Clamp / 35445
• FlyBaseID: FBgn0032979
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_082436.1
• Gene: Zfp558 / 72230
• MGIID: 1921681
• Length: 407
• Species: Mus musculus
• Alignment Length: 318
• Identity: 103/318 - (32%)
• Similarity: 143/318 - (44%)
• Gaps: 84/318 - (26%)

  Fly   276 PQAQAQLQQIVAAQTGGTTPK-----REASSGS--------GHHPVKKRNSQQMTKCQKC----- 322
            |.....|::::.|:  ..|||     :|..:|.        |||.:|      :.:|.:|
Mouse   110 PGIHPDLEKVLKAK--WLTPKNLIFSKEHDNGGKTVQLEERGHHGMK------VNECNQCFKVFS 166

  Fly   323 NGSGVVLVGQHSHASHSGVGGSVKQSVTVKTECLSC----------------RNPSKPFSCNICG 371
            ..|.:.   ||... |:|         ....:|..|                .|..|||.||.||
Mouse   167 TKSNLT---QHKRI-HTG---------EKPYDCTQCGKSFRSKSYLTVHRRIHNGEKPFECNHCG 218

  Fly   372 GLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHAR----------------------- 413
            ..||..|||..|.::|:|||.|:||.|...|..:..||:|.|
Mouse   219 KAFSDPSSLRLHVRIHTGEKPYECSQCFHVFRTSCNLKSHKRIHTGGENQHECSQCGKAFSTRSS 283

  Fly   414 ------IHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHT 472
                  |||||||::||.||..|.:|.:|..|.|||:||:||.|..|.|.|:...:|..|:||||
Mouse   284 LTGHNSIHTGEKPFECQECGKTFRKSSYLTQHLRTHTGEKPYECNECGKSFSSSFSLTVHKRIHT 348

  Fly   473 GEKPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQKY 530
            |||||:|..||.||:..:.:|.|...|:|:|||.|..|..:|.....|..|:.:|.::
Mouse   349 GEKPYECSHCGKAFNNLSAVKKHLMTHTGQKPYGCNHCGKSFTSNSYLSVHKRVHNRW 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	71/167 (43%)
		C2H2 Zn finger	367..387	CDD:275368	10/19 (53%)
		C2H2 Zn finger	395..415	CDD:275368	8/48 (17%)
		zf-H2C2_2	407..432	CDD:463886	16/53 (30%)
		C2H2 Zn finger	423..443	CDD:275368	9/19 (47%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		COG5048	475..>529	CDD:227381	21/53 (40%)
		C2H2 Zn finger	479..499	CDD:275368	7/19 (37%)
		C2H2 Zn finger	507..527	CDD:275368	5/19 (26%)
Zfp558	NP_082436.1	KRAB	43..100	CDD:214630
		COG5048	<125..403	CDD:227381	99/296 (33%)
		C2H2 Zn finger	158..178	CDD:275368	5/23 (22%)
		C2H2 Zn finger	186..206	CDD:275368	2/19 (11%)
		C2H2 Zn finger	214..234	CDD:275368	10/19 (53%)
		C2H2 Zn finger	242..262	CDD:275368	8/19 (42%)
		C2H2 Zn finger	271..291	CDD:275368	0/19 (0%)
		C2H2 Zn finger	299..319	CDD:275368	9/19 (47%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		C2H2 Zn finger	355..375	CDD:275368	7/19 (37%)
		C2H2 Zn finger	383..403	CDD:275368	5/19 (26%)