DRSC/TRiP Functional Genomics Resources

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Protein Alignment Clamp and ikzf4

DIOPT Version :9

Sequence 1:NP_001014498.1 Gene:Clamp / 35445 FlyBaseID:FBgn0032979 Length:566 Species:Drosophila melanogaster
Sequence 2:XP_005162323.1 Gene:ikzf4 / 566844 ZFINID:ZDB-GENE-180319-1 Length:572 Species:Danio rerio


Alignment Length:346 Identity:85/346 - (24%)
Similarity:123/346 - (35%) Gaps:108/346 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly   243 SCMQAEQTAQQQQQLFVAQDGQMAHPVQIISTTPQAQAQLQQIVAAQTGGTTPKREASSGS---- 303
            |.|.....:..:::.|....|...       :||.:|.            ::|.|..|:.|    
Zfish    11 SYMSGSGDSSTEREFFAGLRGPTV-------STPNSQQ------------SSPSRSLSANSIKVE 56

  Fly   304 -------GHHPVKKRNSQQMTKCQK------CNGSGVVLVGQHSHASHSGVGGSVKQSVTVKTEC 355
                   |..|:.:|...:..:..|      ....||.:||.....:.||.|.            
Zfish    57 LYSDEEAGGAPLVERRVGEKDEGWKDEKGDLAEDGGVEMVGGTRGQAGSGCGE------------ 109

  Fly   356 LSCRNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHARIHT---- 416
            ::...|:.|....:..|            ||       ||.|||:.......|..|.|.||    
Zfish   110 MASSEPASPGPIRLPNG------------KL-------KCDICGMICIGPNVLMVHKRSHTVLVS 155

  Fly   417 -GEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIH-----TGEK 475
             ||:|::|..||..|:|..:|..|.:.||||:|:.|..|:....|...|..|.|.|     |..|
Zfish   156 VGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCPFCNYACRRRDALTGHLRTHSVSSPTVGK 220

  Fly   476 PYKCEICGSAFSQAAHLKNH-AKVHS-----------------GEKPYKCEICS----------A 512
            ||||..||.::.|.:.|:.| .:.||                 ||:.:..|:.|          .
Zfish   221 PYKCSYCGRSYKQQSTLEEHRERCHSYLQSLDHQPAHNTQPTHGEESHNVEMISEPLIQSSSEKM 285

  Fly   513 AFADRFA---LKRHRGIHQKY 530
            .|.||.|   .||.|...||:
Zfish   286 TFIDRLANSITKRKRSTPQKF 306

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ClampNP_001014498.1 COG5048 <359..498 CDD:227381 48/149 (32%)
C2H2 Zn finger 367..387 CDD:275368 2/19 (11%)
zf-H2C2_2 379..403 CDD:290200 7/23 (30%)
C2H2 Zn finger 395..415 CDD:275368 7/19 (37%)
zf-H2C2_2 407..432 CDD:290200 12/29 (41%)
C2H2 Zn finger 423..443 CDD:275368 7/19 (37%)
zf-H2C2_2 435..460 CDD:290200 9/24 (38%)
C2H2 Zn finger 451..471 CDD:275368 6/19 (32%)
zf-H2C2_2 464..488 CDD:290200 12/28 (43%)
COG5048 475..>529 CDD:227381 23/84 (27%)
C2H2 Zn finger 479..499 CDD:275368 6/20 (30%)
zf-H2C2_2 491..515 CDD:290200 8/51 (16%)
C2H2 Zn finger 507..527 CDD:275368 9/32 (28%)
ikzf4XP_005162323.1 C2H2 Zn finger 130..150 CDD:275368 7/19 (37%)
zf-H2C2_2 143..172 CDD:290200 12/28 (43%)
COG5048 <146..337 CDD:227381 52/161 (32%)
zf-C2H2 161..183 CDD:278523 7/21 (33%)
C2H2 Zn finger 163..183 CDD:275368 7/19 (37%)
zf-H2C2_2 175..200 CDD:290200 9/24 (38%)
C2H2 Zn finger 191..211 CDD:275368 6/19 (32%)
C2H2 Zn finger 224..245 CDD:275368 6/20 (30%)
C2H2 Zn finger 519..539 CDD:275368
C2H2 Zn finger 547..564 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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