DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Clamp and sug

DIOPT Version :9

Sequence 1:NP_001014498.1 Gene:Clamp / 35445 FlyBaseID:FBgn0032979 Length:566 Species:Drosophila melanogaster
Sequence 2:NP_610826.1 Gene:sug / 36424 FlyBaseID:FBgn0033782 Length:384 Species:Drosophila melanogaster


Alignment Length:287 Identity:77/287 - (26%)
Similarity:112/287 - (39%) Gaps:74/287 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   249 QTAQQQQQLFVAQDGQMAHPVQIISTTPQAQAQLQQIVAAQTGGTTPKREASSGSGHHPVKKRNS 313
            |..|||.|                    |.|.|:|.| ...|...||.|.. :|.|:   ::|..
  Fly    50 QHHQQQHQ--------------------QHQQQMQHI-RFPTPPITPPRPI-AGYGY---RQRTQ 89

  Fly   314 QQMTKCQKCNGSGVVLVGQHSHASHSGVG-GSVKQSVTVKTECLSCRNPSKPFSCN--ICGGLFS 375
            ..:.|.:          ||......|.|. ....:|.:..:||    ..:..|.||  .|..:|.
  Fly    90 SVIMKAR----------GQQDELCRSPVEFPDDSKSCSSSSEC----GTASDFVCNWTDCDRVFD 140

  Fly   376 RYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHARIHTGEKPYKCQTCGMQ-----FSQSPH 435
            ...:|..|                       ..:.||.....:..|.|:..|.|     |:....
  Fly   141 TLDALAQH-----------------------VTQRHAIASLTDGLYYCRWRGCQRSERGFNARYK 182

  Fly   436 LKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKC--EICGSAFSQAAHLKNHAKV 498
            :..|.|||:.|:|:.|.:|:|.|:|...|..|.|.|:|||||||  |.|..|:|.::....|.:.
  Fly   183 MLVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRT 247

  Fly   499 HSGEKPYKCEI--CSAAFADRFALKRH 523
            ||.||||.|::  |...:.|..:|::|
  Fly   248 HSMEKPYMCKVAGCQKRYTDPSSLRKH 274

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ClampNP_001014498.1 COG5048 <359..498 CDD:227381 41/147 (28%)
C2H2 Zn finger 367..387 CDD:275368 6/21 (29%)
zf-H2C2_2 379..403 CDD:290200 2/23 (9%)
C2H2 Zn finger 395..415 CDD:275368 2/19 (11%)
zf-H2C2_2 407..432 CDD:290200 7/29 (24%)
C2H2 Zn finger 423..443 CDD:275368 6/24 (25%)
zf-H2C2_2 435..460 CDD:290200 10/24 (42%)
C2H2 Zn finger 451..471 CDD:275368 8/19 (42%)
zf-H2C2_2 464..488 CDD:290200 14/25 (56%)
COG5048 475..>529 CDD:227381 21/53 (40%)
C2H2 Zn finger 479..499 CDD:275368 6/21 (29%)
zf-H2C2_2 491..515 CDD:290200 9/25 (36%)
C2H2 Zn finger 507..527 CDD:275368 5/19 (26%)
sugNP_610826.1 C2H2 Zn finger 170..190 CDD:275368 4/19 (21%)
zf-H2C2_2 183..207 CDD:290200 10/23 (43%)
COG5048 192..>271 CDD:227381 32/78 (41%)
C2H2 Zn finger 198..218 CDD:275368 8/19 (42%)
zf-H2C2_2 210..237 CDD:290200 14/26 (54%)
C2H2 Zn finger 226..248 CDD:275368 6/21 (29%)
C2H2 Zn finger 256..277 CDD:275368 5/19 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 54 1.000 Inparanoid score I1809
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.050

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