DRSC/TRiP Functional Genomics Resources

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Protein Alignment Clamp and Cf2

DIOPT Version :9

Sequence 1:NP_001014498.1 Gene:Clamp / 35445 FlyBaseID:FBgn0032979 Length:566 Species:Drosophila melanogaster
Sequence 2:NP_001350854.1 Gene:Cf2 / 33692 FlyBaseID:FBgn0000286 Length:537 Species:Drosophila melanogaster


Alignment Length:456 Identity:127/456 - (27%)
Similarity:177/456 - (38%) Gaps:111/456 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    85 LVNGMPLN-QGAALGIATVDAQGRIQIVNQNKPIAANTISNISFKCDVCSDMFPHLALLNAHKRM 148
            |.:|:.|| |||   |||:|. |..|.  |..|       .:|..|..|.:.|.:...|:.|.|:
  Fly    95 LCHGITLNAQGA---IATLDG-GHPQA--QQHP-------KLSHPCFNCDEKFGNAVDLDEHHRL 146

  Fly   149 HTDGEQQQQQQHNAQAGGDSIAVVSAQGL---VQAQNIIGNGQMGQIQIVSSDTLEPVQQSVMQQ 210
                      .|...|......:.|..|:   .|..|.....|.|  .|.::..|...||..|:|
  Fly   147 ----------AHQTPAFLSRCLMCSIYGIHSATQQPNEYKCTQCG--SICTTAMLAAGQQGFMEQ 199

  Fly   211 QQHESKASKCINCGSSMLQQSKRKGPKQVRCESCMQAE-----------QTAQQQQQLFVAQDGQ 264
            |:........:   .:|..:..|..|::...:..:|||           |..||||:|...|..:
  Fly   200 QEAAVTPDDQL---PAMAPRDMRLTPEEQHHQQQLQAEHHHQQQHQQQQQQQQQQQELLEQQQRE 261

  Fly   265 MAHPVQIISTTPQAQAQLQQI-------------VAAQTGGTTPKREASSGSG---HHP--VKKR 311
            |           |.|||.||:             ||.:....|.|...::..|   .||  :.|.
  Fly   262 M-----------QEQAQQQQVHHHQQDQDLAGDQVALKVPPLTVKLNKNANGGAIVSHPQVIIKE 315

  Fly   312 NSQQMTKCQKCNGSGVVLVGQHSHASHSGVGGSVKQSVTVKTECLSCRNPSKPFSCNICGGLFSR 376
            ....::.    :|..|..|..::..::.||.......|.|.|:.:    |:.             
  Fly   316 EPLSLSD----SGDVVNSVPVYAIQANPGVPAPASSGVLVGTQTV----PAD------------- 359

  Fly   377 YSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHARIHTG-------EKPYKCQTCGMQFSQSP 434
                .:||..|      ||..|...|.....|..|.:||||       |:||.|..||..|:||.
  Fly   360 ----LAHKIRH------KCPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCGKSFTQSN 414

  Fly   435 HLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEICGSAFSQAAHLKNH-AKV 498
            .||.|.|.|:||:|:.||.|:|.|:....|..|.|.|||||||.|..|...|:|.:.|..| .|:
  Fly   415 TLKQHTRIHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRFTQRSALTVHTTKL 479

  Fly   499 H 499
            |
  Fly   480 H 480

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ClampNP_001014498.1 COG5048 <359..498 CDD:227381 52/146 (36%)
C2H2 Zn finger 367..387 CDD:275368 2/19 (11%)
zf-H2C2_2 379..403 CDD:290200 6/23 (26%)
C2H2 Zn finger 395..415 CDD:275368 5/19 (26%)
zf-H2C2_2 407..432 CDD:290200 13/31 (42%)
C2H2 Zn finger 423..443 CDD:275368 10/19 (53%)
zf-H2C2_2 435..460 CDD:290200 13/24 (54%)
C2H2 Zn finger 451..471 CDD:275368 8/19 (42%)
zf-H2C2_2 464..488 CDD:290200 13/23 (57%)
COG5048 475..>529 CDD:227381 11/26 (42%)
C2H2 Zn finger 479..499 CDD:275368 7/20 (35%)
zf-H2C2_2 491..515 CDD:290200 4/10 (40%)
C2H2 Zn finger 507..527 CDD:275368
Cf2NP_001350854.1 COG5048 <366..>473 CDD:227381 47/112 (42%)
C2H2 Zn finger 368..388 CDD:275368 5/19 (26%)
C2H2 Zn finger 403..423 CDD:275368 10/19 (53%)
C2H2 Zn finger 431..451 CDD:275368 8/19 (42%)
zf-H2C2_2 443..468 CDD:316026 13/24 (54%)
C2H2 Zn finger 459..480 CDD:275368 7/20 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 54 1.000 Inparanoid score I1809
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.050

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