DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Clamp and CG31441

DIOPT Version :9

Sequence 1:	NP_001014498.1	Gene:	Clamp / 35445	FlyBaseID:	FBgn0032979	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_731558.1	Gene:	CG31441 / 326139	FlyBaseID:	FBgn0051441	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	292	Identity:	79/292 - (27%)
Similarity:	126/292 - (43%)	Gaps:	41/292 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   218 SKCINCGSSMLQQSKRKGPKQVRCESCMQAEQTAQQQQQLFVAQDGQMAHPVQIISTTPQAQAQL 282
            :||:....|.:..:::...|:...:..:......:.||.|:...|.:|.
  Fly    71 NKCLEVHKSFMAANRKLLRKKAIVDEELDKPDVEKLQQDLWDHTDQEMC---------------- 119

  Fly   283 QQIVAAQTGGTTPKREASSGSGHHPVKKRNSQQMTKCQKCNGSGVVLVGQHSHASH--------S 339
              :..|.|.|..  ||..:.:    .|.::::..|:.:| |....|.| |.....|        |
  Fly   120 --VAMADTAGLL--REDHNDN----EKAKDAEDATQNEK-NQEEQVQV-QTEEVEHCQEQLHNMS 174

  Fly   340 GVGGSVKQSVTVKTECLSCRNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAK 404
            .:...|...|..:|:    || ||.:.|:.|||:|...:.|..|.:.|||.|.:.|.||...:..
  Fly   175 IISKGVSARVPKRTK----RN-SKSWFCDQCGGVFKSSTYLKLHLQRHSGHKPFACDICQAKYYT 234

  Fly   405 AVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRR 469
            ...::.|..:||..:||.|:.|...:........|||||:.|||:.|..|||.|...:|...|..
  Fly   235 DNEMRRHRILHTDARPYACRFCSKTYRGCSSKVVHERTHTNERPFQCQHCDKAFTSTSTRQKHEM 299

  Fly   470 IHTGEKPYKCEICGSAFSQAAHLKNH--AKVH 499
            :||.::.|.||||...|.:::||..|  .|:|
  Fly   300 LHTNQRKYHCEICDQWFLRSSHLTLHQSTKLH 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	51/140 (36%)
		C2H2 Zn finger	367..387	CDD:275368	7/19 (37%)
		zf-H2C2_2	379..403	CDD:290200	9/23 (39%)
		C2H2 Zn finger	395..415	CDD:275368	4/19 (21%)
		zf-H2C2_2	407..432	CDD:290200	7/24 (29%)
		C2H2 Zn finger	423..443	CDD:275368	5/19 (26%)
		zf-H2C2_2	435..460	CDD:290200	13/24 (54%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		zf-H2C2_2	464..488	CDD:290200	9/23 (39%)
		COG5048	475..>529	CDD:227381	11/27 (41%)
		C2H2 Zn finger	479..499	CDD:275368	9/21 (43%)
		zf-H2C2_2	491..515	CDD:290200	5/11 (45%)
		C2H2 Zn finger	507..527	CDD:275368
CG31441	NP_731558.1	zf-AD	7..82	CDD:285071	3/10 (30%)
		COG5048	<174..337	CDD:227381	57/163 (35%)
		C2H2 Zn finger	197..217	CDD:275370	7/19 (37%)
		C2H2 Zn finger	225..245	CDD:275368	4/19 (21%)
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		zf-H2C2_2	268..290	CDD:290200	13/21 (62%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	309..328	CDD:275368	8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24381
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100