DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clamp and Zfp13

DIOPT Version :9

Sequence 1:	NP_001014498.1	Gene:	Clamp / 35445	FlyBaseID:	FBgn0032979	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001382483.1	Gene:	Zfp13 / 287095	RGDID:	1304577	Length:	538	Species:	Rattus norvegicus

Alignment Length:	383	Identity:	111/383 - (28%)
Similarity:	166/383 - (43%)	Gaps:	82/383 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   184 IGNG--QMGQ----IQIVSSDTLEPVQQSVMQQQQHESKASKCINCGSSMLQQSKRKGPKQVRCE 242
            :|:|  :||:    :.:.:.:..:|::.........:.|..           |....||......
  Rat   185 LGSGAMEMGKMVPTLAVATLEDTKPIRTRARWAPGEDPKYG-----------QQVASGPATELAR 238

  Fly   243 SCMQAEQTAQQQQQLFVAQDGQMAHPVQIISTTPQAQAQLQQIVAAQTGGTTP-KREASSGSGHH 306
            ...:|.|......:         |||::    ||:.:           |...| :||.:..||..
  Rat   239 DTGEASQLKPAPSE---------AHPLK----TPEYR-----------GPEKPSEREEALTSGEE 279

  Fly   307 PV--KKRNSQQMTKCQKCNGSGVVLVGQHSH-----ASHSGVGGSVKQSVTVKTECLSC------ 358
            .:  .....::..||::| |.|   ...|||     .:|:|     ::..|    |..|
  Rat   280 SLVPDSDTGKKTYKCEQC-GKG---FSWHSHLVTHRRTHTG-----EKPYT----CTDCGKRFGR 331

  Fly   359 ----------RNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHAR 413
                      ....||::|..|...||.:|:|..|:::|:|||.|.|..|...|.:...|..|..
  Rat   332 SSHLIQHQIIHTGEKPYTCPSCWKSFSHHSTLIQHQRIHTGEKPYVCDRCAKRFTRRSDLVTHQG 396

  Fly   414 IHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYK 478
            .|||.||:||..||..|:||..|..|:|||:|.:||.|..|.|.|::.:.|..|.|.|||||||.
  Rat   397 THTGAKPHKCPICGKCFTQSSALVTHQRTHTGVKPYPCPECGKCFSQRSNLIAHNRTHTGEKPYH 461

  Fly   479 CEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQKYGQTAPR 536
            |..||.:||.::||..|.:.|.|.:||.|.:|..:|:.|..|.||..||    .|.|:
  Rat   462 CLDCGKSFSHSSHLTAHQRTHRGVRPYSCPLCGKSFSRRSNLHRHEKIH----TTGPK 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	61/138 (44%)
		C2H2 Zn finger	367..387	CDD:275368	7/19 (37%)
		zf-H2C2_2	379..403	CDD:290200	9/23 (39%)
		C2H2 Zn finger	395..415	CDD:275368	5/19 (26%)
		zf-H2C2_2	407..432	CDD:290200	12/24 (50%)
		C2H2 Zn finger	423..443	CDD:275368	9/19 (47%)
		zf-H2C2_2	435..460	CDD:290200	12/24 (50%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		zf-H2C2_2	464..488	CDD:290200	14/23 (61%)
		COG5048	475..>529	CDD:227381	24/53 (45%)
		C2H2 Zn finger	479..499	CDD:275368	8/19 (42%)
		zf-H2C2_2	491..515	CDD:290200	9/23 (39%)
		C2H2 Zn finger	507..527	CDD:275368	7/19 (37%)
Zfp13	NP_001382483.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000