DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Clamp and IKZF2

DIOPT Version :9

Sequence 1:NP_001014498.1 Gene:Clamp / 35445 FlyBaseID:FBgn0032979 Length:566 Species:Drosophila melanogaster
Sequence 2:XP_011509104.1 Gene:IKZF2 / 22807 HGNCID:13177 Length:533 Species:Homo sapiens


Alignment Length:233 Identity:71/233 - (30%)
Similarity:99/233 - (42%) Gaps:17/233 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   331 GQHSHASHSGVGGSVKQSVTVKTECLSCRNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKC 395
            |||:..||.....|||..:....||     ..||         .||...:..|.:..|.|:....
Human    43 GQHASPSHMTSTNSVKLEMQSDEEC-----DRKP---------LSREDEIRGHDEGSSLEEPLIE 93

  Fly   396 SICGLAFAKAVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFAR 460
            |.......|...|:....|.......||..|||.......|..|:|:|:||||:.|..|...|.:
Human    94 SSEVADNRKVQELQGEGGIRLPNGKLKCDVCGMVCIGPNVLMVHKRSHTGERPFHCNQCGASFTQ 158

  Fly   461 HATLWNHRRIHTGEKPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRG 525
            ...|..|.::|:||||:||..|..|..:...|..|.:.||..||:||..|..::..|.:|:.|:.
Human   159 KGNLLRHIKLHSGEKPFKCPFCSYACRRRDALTGHLRTHSVGKPHKCNYCGRSYKQRSSLEEHKE 223

  Fly   526 IHQKYGQTAPRQTSSDGMIVHKQEIPDMEDEAQQEVII 563
            ....|.|....:.:...|..|   :|.|||..:||.|:
Human   224 RCHNYLQNVSMEAAGQVMSHH---VPPMEDCKEQEPIM 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ClampNP_001014498.1 COG5048 <359..498 CDD:227381 40/138 (29%)
C2H2 Zn finger 367..387 CDD:275368 3/19 (16%)
zf-H2C2_2 379..403 CDD:290200 4/23 (17%)
C2H2 Zn finger 395..415 CDD:275368 3/19 (16%)
zf-H2C2_2 407..432 CDD:290200 7/24 (29%)
C2H2 Zn finger 423..443 CDD:275368 7/19 (37%)
zf-H2C2_2 435..460 CDD:290200 11/24 (46%)
C2H2 Zn finger 451..471 CDD:275368 5/19 (26%)
zf-H2C2_2 464..488 CDD:290200 11/23 (48%)
COG5048 475..>529 CDD:227381 18/53 (34%)
C2H2 Zn finger 479..499 CDD:275368 5/19 (26%)
zf-H2C2_2 491..515 CDD:290200 9/23 (39%)
C2H2 Zn finger 507..527 CDD:275368 5/19 (26%)
IKZF2XP_011509104.1 C2H2 Zn finger 121..141 CDD:275368 7/19 (37%)
zf-H2C2_2 134..158 CDD:290200 11/23 (48%)
COG5048 145..>214 CDD:227381 25/68 (37%)
C2H2 Zn finger 149..169 CDD:275368 5/19 (26%)
zf-H2C2_2 161..186 CDD:290200 11/24 (46%)
C2H2 Zn finger 177..197 CDD:275368 5/19 (26%)
C2H2 Zn finger 205..226 CDD:275368 5/20 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.