DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clamp and M03D4.4

DIOPT Version :9

Sequence 1:	NP_001014498.1	Gene:	Clamp / 35445	FlyBaseID:	FBgn0032979	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001023313.1	Gene:	M03D4.4 / 177375	WormBaseID:	WBGene00019751	Length:	505	Species:	Caenorhabditis elegans

Alignment Length:	291	Identity:	76/291 - (26%)
Similarity:	113/291 - (38%)	Gaps:	72/291 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   319 CQKCNGSGVVL--VGQHSHASHSGVGGSVKQS------------VTVKTE---CLS-------CR 359
            |:.|:|:...|  :.:|....|..|....::.            :.:|.|   .||       ..
Worm     7 CRDCSGAFHSLDELQRHEREEHETVEQGDQEEDRMEDDSDELAMIKIKIEDSDFLSDTDSSQLSM 71

  Fly   360 NPSKPFSCNICGGLFSRYSSLWSHKKLHSGEK-NYKCSICGLAFAKAVYLKNHARIHTGEKPYKC 423
            ||:.|                  .:|..|||| .|:|..|...||....|..|.|||:||:|:.|
Worm    72 NPTTP------------------SEKSSSGEKGRYECEDCHEMFAVKRELATHMRIHSGEQPHSC 118

  Fly   424 QTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEICGSAFSQ 488
            ..||.:|.....||.|...|:|||.:||..|:|.|.:...|..|..||:|.:|::|..|...|..
Worm   119 TQCGKEFGTRQLLKKHWMWHTGERSHVCPHCNKAFFQKGHLTQHLMIHSGGRPHECPQCHKTFIF 183

  Fly   489 AAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHR---------------------GIHQKYGQ 532
            ...|..|.|:|. |:.:.|:.|..:|..:..|..|.                     |:......
Worm   184 KFDLNRHMKIHQ-ERGFSCQQCGRSFLKQVMLDEHHLKCKGKPSSPIRSLLTPTMKAGLESAISI 247

  Fly   533 TAPRQTSSDGMIVHKQEIPDMEDE---AQQE 560
            ..|:::    ||:..:.|..|..:   .|||
Worm   248 KPPQES----MILSSETIAKMAQKLLIQQQE 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	48/139 (35%)
		C2H2 Zn finger	367..387	CDD:275368	1/19 (5%)
		zf-H2C2_2	379..403	CDD:290200	8/24 (33%)
		C2H2 Zn finger	395..415	CDD:275368	7/19 (37%)
		zf-H2C2_2	407..432	CDD:290200	12/24 (50%)
		C2H2 Zn finger	423..443	CDD:275368	7/19 (37%)
		zf-H2C2_2	435..460	CDD:290200	12/24 (50%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		zf-H2C2_2	464..488	CDD:290200	9/23 (39%)
		COG5048	475..>529	CDD:227381	15/74 (20%)
		C2H2 Zn finger	479..499	CDD:275368	6/19 (32%)
		zf-H2C2_2	491..515	CDD:290200	7/23 (30%)
		C2H2 Zn finger	507..527	CDD:275368	6/40 (15%)
M03D4.4	NP_001023313.1	C2H2 Zn finger	90..110	CDD:275368	7/19 (37%)
		zf-H2C2_2	102..127	CDD:290200	12/24 (50%)
		C2H2 Zn finger	118..138	CDD:275368	7/19 (37%)
		C2H2 Zn finger	146..166	CDD:275368	6/19 (32%)
		zf-H2C2_2	158..181	CDD:290200	8/22 (36%)
		zf-C2H2	172..194	CDD:278523	6/21 (29%)
		C2H2 Zn finger	174..194	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000