DRSC/TRiP Functional Genomics Resources

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Protein Alignment Clamp and ZNF765-ZNF761

DIOPT Version :9

Sequence 1:NP_001014498.1 Gene:Clamp / 35445 FlyBaseID:FBgn0032979 Length:566 Species:Drosophila melanogaster
Sequence 2:NP_001337425.1 Gene:ZNF765-ZNF761 / 110116772 -ID:- Length:746 Species:Homo sapiens


Alignment Length:469 Identity:133/469 - (28%)
Similarity:208/469 - (44%) Gaps:81/469 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 QIVNQNKPIA----ANTISNISFKCDVCSDMFPHLALLNAHKRMHTDGEQQQQQQHNAQAGGDSI 169
            ::.||.:.:|    .:|..| .:||:.|...|...:.|..|:|:|| ||:..:.:...:|     
Human   249 KLFNQKRNLACHRRCHTGEN-PYKCNECGKTFSQTSSLTCHRRLHT-GEKPYKCEECDKA----- 306

  Fly   170 AVVSAQGLVQAQNIIGNGQMGQIQIVSSDTLEPVQQSVMQQQQH---ESKASKCINCGSSMLQQS 231
              ...:.:::...||...:..........|..  |:|::.:...   ..|..||..||.:...:|
Human   307 --FHFKSILERHRIIHTEEKPYKCNECGKTFR--QKSILTRHHRLHTGEKPYKCNECGKTFSHKS 367

  Fly   232 K-------RKGPKQVRCESC---------MQAEQTAQQQQQLFVAQDGQMAHPVQIISTTPQAQA 280
            .       ..|.|..:|..|         :...:.....::.:..::...|:..       ::..
Human   368 SLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTGEKPYKCEECDKAYSF-------RSNF 425

  Fly   281 QLQQIVAAQTG-------GTTPKREASSGSGHHPVKKRNSQQMTKCQKCNGSGVVLVGQHSHAS- 337
            ::.:.:..:..       |.|..| .||.:.|.  ::...:|..||::|:.:.........|.. 
Human   426 EIHRKIHTEDNAYKCNECGKTFSR-TSSLTCHR--RRHTGEQPYKCEECDKAFRFKSNLERHRRI 487

  Fly   338 HSGVGGSVKQSVTVKTECLSCRNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAF 402
            |:|                     .||:.||.||..|||.|.|..|.:||:|||.|||:.||..|
Human   488 HTG---------------------EKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTF 531

  Fly   403 AKAVYLKNHARIHTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNH 467
            :....|..|.|:|:|||||||:.||..|:|...||.|.|.||||.||.|...||.::..:.|..|
Human   532 SWKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSNLEIH 596

  Fly   468 RRIHTGEKPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIH----- 527
            ::|||.|.||||..||..||:.:.|..|.::|:||||||||.|..||..:..|:.||.||     
Human   597 QKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRRIHTGEKP 661

  Fly   528 ---QKYGQTAPRQT 538
               .:.|:|..|::
Human   662 YKCNECGKTFSRKS 675

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ClampNP_001014498.1 COG5048 <359..498 CDD:227381 67/138 (49%)
C2H2 Zn finger 367..387 CDD:275368 10/19 (53%)
zf-H2C2_2 379..403 CDD:290200 12/23 (52%)
C2H2 Zn finger 395..415 CDD:275368 7/19 (37%)
zf-H2C2_2 407..432 CDD:290200 14/24 (58%)
C2H2 Zn finger 423..443 CDD:275368 9/19 (47%)
zf-H2C2_2 435..460 CDD:290200 13/24 (54%)
C2H2 Zn finger 451..471 CDD:275368 5/19 (26%)
zf-H2C2_2 464..488 CDD:290200 13/23 (57%)
COG5048 475..>529 CDD:227381 27/61 (44%)
C2H2 Zn finger 479..499 CDD:275368 7/19 (37%)
zf-H2C2_2 491..515 CDD:290200 13/23 (57%)
C2H2 Zn finger 507..527 CDD:275368 8/19 (42%)
ZNF765-ZNF761NP_001337425.1 KRAB 7..48 CDD:307490
C2H2 Zn finger 217..237 CDD:275368
COG5048 242..617 CDD:227381 110/409 (27%)
C2H2 Zn finger 244..264 CDD:275368 3/14 (21%)
C2H2 Zn finger 272..292 CDD:275368 6/19 (32%)
C2H2 Zn finger 300..320 CDD:275368 2/26 (8%)
C2H2 Zn finger 328..348 CDD:275368 3/21 (14%)
C2H2 Zn finger 356..376 CDD:275368 4/19 (21%)
C2H2 Zn finger 384..404 CDD:275368 2/19 (11%)
C2H2 Zn finger 412..432 CDD:275368 1/26 (4%)
C2H2 Zn finger 440..460 CDD:275368 6/22 (27%)
C2H2 Zn finger 468..488 CDD:275368 3/19 (16%)
C2H2 Zn finger 496..516 CDD:275368 10/19 (53%)
C2H2 Zn finger 524..544 CDD:275368 7/19 (37%)
C2H2 Zn finger 552..572 CDD:275368 9/19 (47%)
C2H2 Zn finger 580..600 CDD:275368 5/19 (26%)
C2H2 Zn finger 608..628 CDD:275368 7/19 (37%)
C2H2 Zn finger 636..656 CDD:275368 8/19 (42%)
SFP1 <651..737 CDD:227516 7/25 (28%)
C2H2 Zn finger 664..684 CDD:275368 3/12 (25%)
C2H2 Zn finger 692..712 CDD:275368
C2H2 Zn finger 720..740 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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