DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clamp and si:ch211-229l10.11

DIOPT Version :9

Sequence 1:	NP_001014498.1	Gene:	Clamp / 35445	FlyBaseID:	FBgn0032979	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	XP_021331165.1	Gene:	si:ch211-229l10.11 / 103910550	ZFINID:	ZDB-GENE-110913-131	Length:	850	Species:	Danio rerio

Alignment Length:	419	Identity:	124/419 - (29%)
Similarity:	187/419 - (44%)	Gaps:	78/419 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 FKCDVCSDMFPHLALLNAHKRMHTDGEQQQQQQHNAQAGGDSIAVVSAQGLVQAQNIIGNGQMGQ 191
            :.|..|...|.|.....||:|:|| ||::...||..::       .|..|.:.....|..|:
Zfish    38 YTCQQCGKSFYHAGNFAAHQRIHT-GERKYTCQHCGKS-------FSKTGNLAVHMRIHTGE--- 91

  Fly   192 IQIVSSDTLEPVQQSVMQQQQHESKASKCINCGSSMLQQSKRK----GPKQVRCESCMQAEQTAQ 252
                                    |...|..||.|..|....|    ...:.|..:|.|..::..
Zfish    92 ------------------------KPYSCSQCGKSFKQNVTLKIHMRTHNEERIFTCTQCGKSIS 132

  Fly   253 QQQQLFVAQDGQMAHPVQIISTTPQAQAQLQQIVAAQTGGTTPKREASSGS-GHHPVKKRNSQQM 316
            |:..|.:   ....|..:            :.....:.|.:.|.:    || .||.:.....:..
Zfish   133 QKHYLDI---NMRIHTGE------------KPYTCTECGKSFPYK----GSLKHHRISHTGEKPF 178

  Fly   317 TKCQKCNGSGVVLVGQHSHAS-----HSG--------VGGSVKQSVTVKTECLSCRNPSKPFSCN 368
            | |.:|..:    ..|.||.:     |:|        .|.|...|..: .:.:......|||:|.
Zfish   179 T-CTQCGKN----FNQSSHLNQHMRIHTGEKPFTCTQCGKSFSYSANL-NQHMRIHTGEKPFTCT 237

  Fly   369 ICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHARIHTGEKPYKCQTCGMQFSQS 433
            .||..||..::|..|.::|:|||.:.|:.||.:|:::.||..|.||||||||:.|..||..||||
Zfish   238 QCGKSFSNSANLNQHMRIHTGEKPFTCTQCGKSFSQSSYLNQHMRIHTGEKPFTCTQCGKSFSQS 302

  Fly   434 PHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEICGSAFSQAAHLKNHAKV 498
            |:|..|.|.|:||:|:.|..|.|.|::.::|:.|.||||||||:.|..||.:||::::|..|.:.
Zfish   303 PYLNQHMRIHTGEKPFTCSQCGKSFSQSSSLYLHMRIHTGEKPFTCTQCGKSFSKSSNLNIHMRN 367

  Fly   499 HSGEKPYKCEICSAAFADRFALKRHRGIH 527
            |:||||:.|..|..:|:...:|..|..||
Zfish   368 HTGEKPFTCLQCGKSFSQSTSLNLHMRIH 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	65/138 (47%)
		C2H2 Zn finger	367..387	CDD:275368	7/19 (37%)
		zf-H2C2_2	379..403	CDD:290200	9/23 (39%)
		C2H2 Zn finger	395..415	CDD:275368	8/19 (42%)
		zf-H2C2_2	407..432	CDD:290200	15/24 (63%)
		C2H2 Zn finger	423..443	CDD:275368	11/19 (58%)
		zf-H2C2_2	435..460	CDD:290200	11/24 (46%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		zf-H2C2_2	464..488	CDD:290200	14/23 (61%)
		COG5048	475..>529	CDD:227381	21/53 (40%)
		C2H2 Zn finger	479..499	CDD:275368	7/19 (37%)
		zf-H2C2_2	491..515	CDD:290200	9/23 (39%)
		C2H2 Zn finger	507..527	CDD:275368	5/19 (26%)
si:ch211-229l10.11	XP_021331165.1	C2H2 Zn finger	12..32	CDD:275368
		zf-H2C2_2	25..49	CDD:316026	3/10 (30%)
		C2H2 Zn finger	40..60	CDD:275368	7/19 (37%)
		C2H2 Zn finger	68..88	CDD:275368	4/26 (15%)
		zf-H2C2_2	80..105	CDD:316026	7/51 (14%)
		SFP1	<90..169	CDD:227516	19/124 (15%)
		C2H2 Zn finger	96..116	CDD:275368	6/19 (32%)
		C2H2 Zn finger	124..144	CDD:275368	4/22 (18%)
		C2H2 Zn finger	152..172	CDD:275368	6/23 (26%)
		COG5048	176..580	CDD:227381	88/227 (39%)
		C2H2 Zn finger	180..200	CDD:275368	5/23 (22%)
		C2H2 Zn finger	208..228	CDD:275368	3/20 (15%)
		C2H2 Zn finger	236..256	CDD:275368	7/19 (37%)
		C2H2 Zn finger	264..284	CDD:275368	8/19 (42%)
		C2H2 Zn finger	292..312	CDD:275368	11/19 (58%)
		C2H2 Zn finger	320..340	CDD:275368	7/19 (37%)
		C2H2 Zn finger	348..368	CDD:275368	7/19 (37%)
		C2H2 Zn finger	376..396	CDD:275368	5/19 (26%)
		COG5048	400..841	CDD:227381
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368
		C2H2 Zn finger	488..508	CDD:275368
		C2H2 Zn finger	517..537	CDD:275368
		C2H2 Zn finger	545..565	CDD:275368
		C2H2 Zn finger	573..593	CDD:275368
		C2H2 Zn finger	601..621	CDD:275368
		C2H2 Zn finger	629..649	CDD:275368
		C2H2 Zn finger	657..677	CDD:275368
		C2H2 Zn finger	685..705	CDD:275368
		C2H2 Zn finger	713..733	CDD:275368
		C2H2 Zn finger	741..761	CDD:275368
		C2H2 Zn finger	769..789	CDD:275368
		C2H2 Zn finger	797..817	CDD:275368
		C2H2 Zn finger	825..845	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24381
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100