DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clamp and ikzf3

DIOPT Version :9

Sequence 1:	NP_001014498.1	Gene:	Clamp / 35445	FlyBaseID:	FBgn0032979	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	XP_031750661.1	Gene:	ikzf3 / 100491406	XenbaseID:	XB-GENE-994462	Length:	377	Species:	Xenopus tropicalis

Alignment Length:	154	Identity:	50/154 - (32%)
Similarity:	75/154 - (48%)	Gaps:	22/154 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   417 GEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEI 481
            ||:|::|..||..|:|..:|..|.:.|:||:|:.|.:|.....|...|..|.|.|:.|||||||.
Frog    16 GERPFQCNQCGASFTQKGNLLRHGKLHTGEKPFKCHLCSYACQRRDALTGHLRTHSVEKPYKCEF 80

  Fly   482 CGSAFSQAAHLKNHAK---------------VHSGEKPYKCEICS--AAFADRFA---LKRHRGI 526
            ||.::.|.:.|:.|.:               .....:|.|.|:.|  |...||.|   .||...:
Frog    81 CGRSYKQRSSLEEHKERCRIYQQNLSESATAASEDSRPPKPEMGSERALVLDRLASNVAKRKSTM 145

  Fly   527 HQKY-GQTAP-RQTSSDGMIVHKQ 548
            .||: |:..| .:.|.:|.:..|:
Frog   146 PQKFIGEKQPCFEISYNGYLYDKE 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	33/95 (35%)
		C2H2 Zn finger	367..387	CDD:275368
		zf-H2C2_2	379..403	CDD:290200
		C2H2 Zn finger	395..415	CDD:275368
		zf-H2C2_2	407..432	CDD:290200	7/14 (50%)
		C2H2 Zn finger	423..443	CDD:275368	7/19 (37%)
		zf-H2C2_2	435..460	CDD:290200	8/24 (33%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		zf-H2C2_2	464..488	CDD:290200	13/23 (57%)
		COG5048	475..>529	CDD:227381	21/73 (29%)
		C2H2 Zn finger	479..499	CDD:275368	7/34 (21%)
		zf-H2C2_2	491..515	CDD:290200	7/40 (18%)
		C2H2 Zn finger	507..527	CDD:275368	8/24 (33%)
ikzf3	XP_031750661.1	COG5048	<19..153	CDD:227381	44/133 (33%)
		C2H2 Zn finger	22..42	CDD:275368	7/19 (37%)
		C2H2 Zn finger	50..70	CDD:275368	6/19 (32%)
		C2H2 Zn finger	78..94	CDD:275368	6/15 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910