Protein Alignment Clamp and LOC100485124

DIOPT Version :10

• Sequence 1: NP_001014498.1
• Gene: Clamp / 35445
• FlyBaseID: FBgn0032979
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_002938535.1
• Gene: LOC100485124 / 100485124
• XenbaseID: XB-GENE-29077627
• Length: 529
• Species: Xenopus tropicalis
• Alignment Length: 506
• Identity: 113/506 - (22%)
• Similarity: 194/506 - (38%)
• Gaps: 108/506 - (21%)

  Fly    96 ALGIATVDAQGRIQIVNQNKPIAANTISNISFKCDVCSDMFPHLALLNAHKRMHTD-GEQQQQQQ 159
            :||...::....::|..:::|...:  .|:..:.:..:...|...|:|....:... ||:|....
 Frog    47 SLGFIILNPNNFLRIQPEDEPCLKS--RNVLERNESINITEPDCGLVNPDILLTVQLGEKQHVAD 109

  Fly   160 HNAQAGGDSIAVVSAQGLV----------QAQNIIGNGQMGQIQIVSSDTL-----EPVQQSVMQ 209
            ...:.||.::::.|....:          |..::.....:..::.::|...     |||.:.|..
 Frog   110 TYEENGGRNVSLPSTSKFIDKFGEYTAVKQEAHLADYTSIPNVKPLNSPKKRYPCNEPVLRRVSI 174

  Fly   210 QQQHESKASKCINCGSSMLQQSKRKGPKQVRCESCMQAEQTAQQQQQLFVAQDGQMAHPVQIIST 274
            |:|           .|:.|....::|.:.    |.:|..:.:...    :::...:|.|.:.|..
 Frog   175 QEQ-----------PSNSLHLELKRGIRY----STVQGNRASTSG----LSKPNAVAVPGKFIIK 220

  Fly   275 TP----------QAQAQLQQIVAAQTGGTTPKR-EASSGSGHHPVKKRN------SQQMTKCQKC 322
            .|          :|..:::.:.........|.. |..|..|...|...|      .:|:|  ||.
 Frog   221 KPYNMCDKNFNVKAYPKIEPLTLKVKSKELPSNTENVSLEGRKMVNYINVDETISERQVT--QKL 283

  Fly   323 NGSGVVLVG----QHSHASHSGVGGSVKQSVTVKTECLSCR---------NPSKPFSCNICGGLF 374
            |...:.|..    |::..|.......::.|:|.|.|....|         .|.:.|:|..||..|
 Frog   284 NLGNIPLKNKGKVQYNLKSSGYCQRMLRWSITQKEEVTQKRYLAGAQVSKEPERSFNCTECGKRF 348

  Fly   375 SRYSSLWSHKKLHSGEKNYK------CSICGLAFAKAVYLKNHARIH------------------ 415
            .:.|.|    :||.|....|      |         .:.||:|..:.
 Frog   349 LKLSDL----RLHQGSHRIKIKQLNGC---------VIQLKSHQNVQASQRLSIEQKNSNTGSPK 400

  Fly   416 --TGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYK 478
              :|.|...|...|...|.:.|:..|::|...||.:||..|.|.|..::.|..|.||||||||::
 Frog   401 NISGAKSLTCAVYGKNVSPNTHVVPHQKTLVRERRFVCKFCGKRFQNNSNLIGHERIHTGEKPFE 465

  Fly   479 CEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQK 529
            |..||.:|||.|:|..|.::|:||:|:.|..|...||.:..|..|...|.|
 Frog   466 CPECGKSFSQKANLTTHQRLHTGERPFVCITCGKGFAQKINLLTHEQTHAK 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	51/173 (29%)
		C2H2 Zn finger	367..387	CDD:275368	6/19 (32%)
		C2H2 Zn finger	395..415	CDD:275368	4/19 (21%)
		zf-H2C2_2	407..432	CDD:463886	7/44 (16%)
		C2H2 Zn finger	423..443	CDD:275368	5/19 (26%)
		C2H2 Zn finger	451..471	CDD:275368	7/19 (37%)
		COG5048	475..>529	CDD:227381	22/53 (42%)
		C2H2 Zn finger	479..499	CDD:275368	9/19 (47%)
		C2H2 Zn finger	507..527	CDD:275368	6/19 (32%)
LOC100485124	XP_002938535.1	KRAB	9..68	CDD:214630	3/20 (15%)
		C2H2 Zn finger	339..361	CDD:275369	10/25 (40%)
		COG5048	<375..525	CDD:227381	49/142 (35%)
		C2H2 Zn finger	410..430	CDD:275368	5/19 (26%)
		C2H2 Zn finger	438..458	CDD:275368	7/19 (37%)
		zf-H2C2_2	450..475	CDD:463886	14/24 (58%)
		C2H2 Zn finger	466..486	CDD:275368	9/19 (47%)
		C2H2 Zn finger	494..514	CDD:275368	6/19 (32%)