Protein Alignment Clamp and Zfp729b

DIOPT Version :10

• Sequence 1: NP_001014498.1
• Gene: Clamp / 35445
• FlyBaseID: FBgn0032979
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001388788.1
• Gene: Zfp729b / 100416706
• MGIID: 2145180
• Length: 1055
• Species: Mus musculus
• Alignment Length: 436
• Identity: 133/436 - (30%)
• Similarity: 195/436 - (44%)
• Gaps: 56/436 - (12%)

  Fly   127 FKCDVCSDMFPHLALLNAHKRMHTDGEQQQQQQHNAQAGGDSIAVVSAQGLVQAQNIIGNGQMGQ 191
            :||:||...|.|.:.|:.||::|:     :::.:..:..|.:....|   |:.....:..|:
Mouse   170 YKCEVCGKAFQHPSRLSRHKKIHS-----EEKPYKCEVCGKAFHFPS---LLLVHKRVHTGE--- 223

  Fly   192 IQIVSSDTLEPVQQSVMQQQQH-------------ESKASKCINCG-----SSMLQQSK--RKGP 236
                     :|.:..|..:..|             ..|..||..||     ||.|.:.|  .:|.
Mouse   224 ---------KPYKCEVCGKAFHYPSILSKHKRIHTGEKPYKCEECGKAFHISSFLSKHKIIHRGE 279

  Fly   237 KQVRCESCMQAEQTAQQQQQLFVAQDGQMAHPVQIISTTPQAQAQLQQIVAAQTGGTTPKREASS 301
            |..:||.|.:|.....:..........:..:..:|.....:..:.|.:.....|.....|.|...
Mouse   280 KPYKCEVCGKAFHYPSRLSNHKKIHSVEKPYKCEICGKAFRILSLLSKHKIIHTEENPYKCEVCG 344

  Fly   302 GSGHHP------VKKRNSQQMTKCQKCNGS--GVVLVGQHS--HASHSGVGGSVKQSVTVKTECL 356
            .:..:|      .|....::..||:.|..:  .:..:.:|.  |...:.....:..:..|....|
Mouse   345 KAFDYPSRLSTHAKMHTGEKPYKCEVCEKAFRSLSSLSKHRRIHMGDNYYNSELCSNAFVYPSRL 409

  Fly   357 S-----CRNPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHARIHT 416
            |     ||. .||:.|.:||..|...|.|..|:.:|:|||.|||.:||.||.....|..|.||||
Mouse   410 SKHKKICRG-EKPYKCEVCGKAFHVSSLLSKHRTIHTGEKLYKCEVCGKAFYYPSRLSTHKRIHT 473

  Fly   417 GEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGEKPYKCEI 481
            |||||||:.||..|...|.|..|:|.|:||:||.|..|.|.|...::|..|::|||||||||||:
Mouse   474 GEKPYKCEVCGKAFCFPPSLSKHKRIHTGEKPYKCKECGKAFRFPSSLSAHKKIHTGEKPYKCEV 538

  Fly   482 CGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIH 527
            ||.||...:.|..|..:|:|||||||:||..||.....|..|:.||
Mouse   539 CGKAFHYPSLLSKHKIIHTGEKPYKCDICDQAFHVPSKLSHHKIIH 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clamp	NP_001014498.1	COG5048	<359..498	CDD:227381	69/138 (50%)
		C2H2 Zn finger	367..387	CDD:275368	7/19 (37%)
		C2H2 Zn finger	395..415	CDD:275368	8/19 (42%)
		zf-H2C2_2	407..432	CDD:463886	16/24 (67%)
		C2H2 Zn finger	423..443	CDD:275368	8/19 (42%)
		C2H2 Zn finger	451..471	CDD:275368	6/19 (32%)
		COG5048	475..>529	CDD:227381	28/53 (53%)
		C2H2 Zn finger	479..499	CDD:275368	8/19 (42%)
		C2H2 Zn finger	507..527	CDD:275368	7/19 (37%)
Zfp729b	NP_001388788.1	KRAB	15..73	CDD:214630
		C2H2 Zn finger	88..136	CDD:275368
		SFP1	<96..207	CDD:227516	11/41 (27%)
		C2H2 Zn finger	144..164	CDD:275368
		C2H2 Zn finger	172..192	CDD:275368	8/19 (42%)
		C2H2 Zn finger	200..220	CDD:275368	3/22 (14%)
		COG5048	224..653	CDD:227381	119/362 (33%)
		C2H2 Zn finger	228..248	CDD:275368	2/19 (11%)
		C2H2 Zn finger	256..276	CDD:275368	7/19 (37%)
		C2H2 Zn finger	284..304	CDD:275368	4/19 (21%)
		C2H2 Zn finger	312..332	CDD:275368	2/19 (11%)
		C2H2 Zn finger	340..360	CDD:275368	3/19 (16%)
		C2H2 Zn finger	368..388	CDD:275368	3/19 (16%)
		C2H2 Zn finger	424..444	CDD:275368	7/19 (37%)
		C2H2 Zn finger	452..472	CDD:275368	8/19 (42%)
		COG5048	476..889	CDD:227381	56/109 (51%)
		C2H2 Zn finger	480..500	CDD:275368	8/19 (42%)
		C2H2 Zn finger	508..528	CDD:275368	6/19 (32%)
		C2H2 Zn finger	536..556	CDD:275368	8/19 (42%)
		C2H2 Zn finger	564..584	CDD:275368	7/19 (37%)
		C2H2 Zn finger	592..612	CDD:275368
		C2H2 Zn finger	620..640	CDD:275368
		C2H2 Zn finger	648..668	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	705..724	CDD:275368
		C2H2 Zn finger	732..752	CDD:275368
		C2H2 Zn finger	760..780	CDD:275368
		C2H2 Zn finger	788..808	CDD:275368
		C2H2 Zn finger	816..836	CDD:275368
		C2H2 Zn finger	844..864	CDD:275368
		C2H2 Zn finger	872..892	CDD:275368
		C2H2 Zn finger	900..920	CDD:275368
		C2H2 Zn finger	928..948	CDD:275368
		SFP1	<950..1029	CDD:227516
		C2H2 Zn finger	956..976	CDD:275368
		C2H2 Zn finger	984..1004	CDD:275368
		C2H2 Zn finger	1012..1032	CDD:275368